2018—2020年昆明市男男性行为人群HIV新发感染队列研究  

Cohort study of new HIV infections among men who have sex with men in Kunming from 2018 to 2020

作　　者：蔡永年 李佑芳[1] 王珏[1] 马婧[1] 潘颂峰[1] 李志晴[1] 王玉淼 马艳玲[1] CAI Yongnian;LI Youfang;WANG Jue;MA Jing;PAN Songfeng;LI Zhiqing;WANG Yumiao;MA Yanling(Yiunnan center for disease control and prevention,Kunming,Yunnan 650022,Ch ina)

机构地区：[1]云南省疾病预防控制中心,云南昆明650022

出　　处：《中国公共卫生管理》2023年第1期77-80,共4页Chinese Journal of Public Health Management

基　　金：国家“十三五”科技重大专项(2018ZX10715-006)。

摘　　要：目的了解昆明市男男性行为人群(MSM)HIV新发感染率及影响因素。方法2018年6—12月通过云南省昆明市某社会组织招募204名MSM,建立队列并进行问卷调查和血清学检测,采用Cox模型分析HIV新发感染的影响因素。结果204名MSM中,艾滋病知识知晓率为97.55%,近1个月、3个月、6个月发生性行为时全程正确使用安全套的占比分别为68.38%、68.85%、67.20%,近6个月使用过助兴剂者占17.16%。HIV新发感染率为2.78/100人年。婚姻状况为分居、离异、丧偶,近3个月不使用或较少使用安全套是MSM感染的危险因素。结论与昆明市2012—2016年的研究结果相比,2018—2020年MSM新发感染率有所下降,昆明市MSM存在一定程度的知行分离。应继续加强MSM行为干预,加强艾滋病、安全套、新型毒品和助兴剂相关知识健康教育,并推广使用暴露后预防及暴露前预防,尤需关注长期分居、离婚、丧偶的MSM。Objective To understand the rate of new HIV infections and factors influencing it in the men who have sex with men population(MSM)in Kunming.Methods From June to December 2018,204 MSM were recruited through a social organization in Kunming,Yunnan Province,and a cohort was established and subjected to questionnaires and serological testing.Cox models were used to analyze the influencing factors of new HIV infections.Results Among the 204 MSM,the knowledge rate of HIV was 97.55%,and the percentages of those who had used condoms correctly throughout the last 1,3,and 6 months when having sex were 68.38%,68.85%,and 67.20%,respectively,and 17.16%of those who had used a booster in the last 6 months.The rate of new HIV infections was 2.78/100 person-years.Marital status of separation,divorce,widowhood,and non-use or lesser use of condoms in the last 3 months were risk factors for MSM infection.Conclusion Compared with the results of the 2012-2016 study in Kunming,the rate of new MSM infections decreased in 2018—2020,and there was a certain degree of knowledge-activity separation of MSM in Kunming.Behavioral interventions for MSM should continue to be strengthened,health education on HIV,condoms,new drugs and stimulants should be enhanced,and the use of post-exposure prophylaxis and pre-exposure prophylaxis should be promoted,with special attention to MSM who are separated,divorced or widowed for a long time.

关 键 词：男男性行为人群 HIV 队列研究 昆明 

分 类 号：R512.93[医药卫生—内科学]