Youden图在精子浓度室间质量评价中的应用  

Role of Youden plot in external quality assessment of sperm concentration

作　　者：张为民[1] 李婷[1] 张琛[1] 谢楠[1] 赵飞[1] 吴霞[1] 孟庆昊 李敏[1] 高选[1] 杨斯桀 ZHANG Weimin;LI Ting;ZHANG Chen;XIE Nan;ZHAO Fei;WU Xia;MENG Qinghao;LI Min;GAO Xuan;YANG Sijie(Center of Reproductive Medicine,the National Research Center for Assisted Reproductive Technology and Reproductive Genetics,the Key Laboratory of the Ministry of Education for Reproductive Endocrinology,Shandong University,Jinan 250001,Shandong,China)

机构地区：[1]山东大学生殖医学研究中心国家辅助生殖与优生工程技术研究中心生殖内分泌教育部重点实验室(山东大学),山东济南250001

出　　处：《检验医学》2023年第2期167-171,共5页Laboratory Medicine

基　　金：山东省医药卫生科技发展计划(2019WS173)。

摘　　要：目的根据精子浓度室间质量评价(EQA)数据绘制Youden图,以通过EQA回报结果获取更多有效信息,发现系统误差,改进实验室检测质量。方法收集2019和2020年山东省精子浓度EQA数据,绘制Youden图,分析2019和2020年EQA回报结果。结果Youden图显示,2020年低浓度水平质控品变异系数(CV)为31%,显著低于2019年(19%)(P<0.05);高浓度水平质控品CV差异无统计学意义(P=0.097)。结论Youden图可以反映精液分析项目实验室系统误差的趋势,帮助临床实验室更直观地发现系统误差。Objective According to Youden plot in external quality assessment(EQA)of sperm concentration,to bring more efficient information from EQA report data,to discover systematical errors,and to improve determination quality.Methods The sperm concentration EQA data of Shandong province in 2019 and 2020 were collected,a Youden plot had been drawn,and the EQA report results of 2019 and 2020 were analyzed.Results The coefficient of variation(CV)of quality control meterial at low concentration levels in 2020(31%)was decreased compared with that in 2019(19%)(P<0.05),and the CV of quality control meterial at high concentration levels had no statistical significance(P=0.097).Conclusions Youden plot can reflect the tendency of laboratory systematical errors for sperm concentration,so the participating laboratories can find the systematical errors directly.

关 键 词：精子浓度 精液分析 室间质量评价 系统误差 Youden图 

分 类 号：R446.1[医药卫生—诊断学]