急性ST段抬高心肌梗死患者直接经皮冠状动脉介入治疗后微血管功能障碍再认识  

Coronary Microvascular Dysfunction in Patients with Acute ST Segment Elevation Myocardial Infarction After Primary Percutaneous Coronary Intervention

作　　者：李明[1] 张慧平[1] LI Ming;ZHANG Huiping(Department of Cardiology,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京医院心血管内科、国家老年医学中心、中国医学科学院老年医学研究院,北京100730

出　　处：《心血管病学进展》2023年第3期193-197,共5页Advances in Cardiovascular Diseases

基　　金：中央高水平医院临床科研业务费资助(BJ-2018-201)。

摘　　要：直接经皮冠状动脉介入治疗(PPCI)是急性ST段抬高心肌梗死的首选再灌注治疗策略。研究表明,急性ST段抬高心肌梗死患者在行PPCI后可能会出现冠状动脉微血管功能障碍,导致冠状动脉慢血流或无复流,与不良预后相关。现对急性ST段抬高心肌梗死患者接受PPCI后发生冠状动脉微血管功能障碍的病理生理机制、微血管功能状态评估及治疗策略进行综述。Primary percutaneous coronary intervention(PPCI)is the preferred reperfusion strategy for acute ST segment elevation myocardial infarction(STEMI).Studies have shown that coronary microvascular dysfunction may occur in patients with STEMI after PPCI,resulting in slow-flow or no-reflow of coronary arteries,which is associated with poor prognosis.This article reviews the pathophysiology,assessment of microvascular functional status and treatment strategies for coronary microvascular dysfunction in patients with STEMI after PPCI.

关 键 词：冠状动脉 急性ST段抬高心肌梗死 直接经皮冠状动脉介入治疗 微血管功能障碍 

分 类 号：R542.22[医药卫生—心血管疾病]