红细胞在脂质代谢和动脉粥样硬化中的研究进展  

Red Blood Cell in Lipid Metabolism and Atherosclerosis

作　　者：耿超强 高奋[2] GENG Chaoqiang;GAO Fen(Shanxi Medical University,Taiyuan 030001,Shanxi,China;Cardiovascular Department,The Second Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi,China)

机构地区：[1]山西医科大学,山西太原030001 [2]山西医科大学第二医院心内科,山西太原030001

出　　处：《心血管病学进展》2023年第3期256-259,264,共5页Advances in Cardiovascular Diseases

基　　金：山西省重点研发计划项目(201903D321185)。

摘　　要：动脉粥样硬化的形成和进展涉及脂质蓄积、氧化应激以及炎症反应等机制。红细胞是体内的重要组成成分,主要功能是与全身组织进行气体交换。红细胞长期以来一直被认为是动脉粥样硬化的旁观者。而最新研究发现红细胞是血浆脂质代谢的参与者,并且参与动脉粥样硬化的形成和进展。现介绍红细胞的结构和生理功能,并着重讨论红细胞对动脉粥样硬化的影响。The formation and progress of atherosclerosis involves lipid accumulation,oxidative stress and inflammation.Red blood cell is an important component of the body whose main function is to exchange gas with tissues throughout the body.Red blood cell has long been considered bystanders of atherosclerosis.However,recent studies have found that red blood cell is participant in plasma lipid metabolism and participate in the formation and progress of atherosclerosis.This review introduces the structure and physiological functions of red blood cell,and focuses on the effect of red blood cell on atherosclerosis.

关 键 词：红细胞 动脉粥样硬化 胆固醇逆转运 胆固醇 

分 类 号：R54[医药卫生—心血管疾病]