补肾疏肝法针刺治疗肾虚肝郁型围绝经期失眠的临床观察  

Clinical Observation on Acupuncture for Tonifying the Kidney and Soothing the Liver in the Treatment of Perimenopausal Insomnia with Kidney Deficiency and Liver Depression Syndrome

作　　者：王静 冉琴[3] 赵玉华 罗文澜 李陈渝 李航[2] 杨进[1,2] WANG Jing;RAN Qin;ZHAO Yu-Hua;LUO Wen-Lan;LI Chen-Yu;LI Hang;YANG Jin(Guizhou University of Traditional Chinese Medicine,Guiyang 550002 Guizhou,China;Chongqing Hospital of Traditional Chinese Medicine,Chongqing 400021,China;Guiyang Wudang District People's Hospital,Guiyang 550002 Guizhou,China)

机构地区：[1]贵州中医药大学,贵州贵阳550002 [2]重庆市中医院,重庆400021 [3]贵阳市乌当区人民医院,贵州贵阳550002

出　　处：《广州中医药大学学报》2023年第3期652-658,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：重庆市卫生健康委中医药科技资助项目(编号:ZY201702016);重庆市科研机构绩效激励引导专项资助项目(编号:cstc2019jxj1130016)。

摘　　要：【目的】观察补肾疏肝法针刺治疗肾虚肝郁型围绝经期失眠的临床疗效。【方法】将50例肾虚肝郁型围绝经期失眠患者随机分为观察组和对照组,每组各25例。对照组给予佐匹克隆片口服,观察组给予补肾疏肝法针刺治疗。连续治疗2周。治疗2周后,评价2组临床疗效,观察2组患者治疗前后中医证候积分的变化情况,以及匹兹堡睡眠质量指数量表(PSQI)评分的情况。比较2组患者治疗前后汉密尔顿焦虑量表(HAMA)-14评分与汉密尔顿抑郁量表(HAMD)-17评分的变化情况。【结果】(1)观察组总有效率为88.00%(22/25),对照组为76.00%(19/25)。观察组疗效稍优于对照组,但差异无统计学意义(P>0.05)。(2)治疗后,2组患者的中医证候总积分明显改善(P<0.05),且观察组在改善中医证候总积分方面明显优于对照组,差异有统计学意义(P<0.05)。(3)治疗后,2组患者的PSQI各项目评分及总积分明显改善(P<0.05),且观察组在改善睡眠效率、日间功能障碍及总积分方面明显优于对照组,差异有统计学意义(P<0.05)。(4)治疗后,2组患者的HAMA-14积分明显改善(P<0.05),且观察组在改善HAMA-14积分方面明显优于对照组,差异有统计学意义(P<0.05)。(5)治疗后,2组患者的HAMD-17积分明显改善(P<0.05),观察组在改善HAMD-17积分方面稍优于对照组,但差异无统计学意义(P>0.05)。【结论】补肾疏肝法针刺治疗肾虚肝郁型围绝经期失眠,能有效改善患者的失眠症状,提高睡眠效率和质量,从而提高患者生活质量,疗效显著。Objective To observe the clinical efficacy of acupuncture for tonifying the kidney and soothing the liver in treating kidney deficiency and liver depression type of perimenopausal insomnia(PMI). Methods Fifty PMI patients of kidney deficiency and liver depression type were randomly divided into the observation group and the control group,with 25 cases in each group. The control group was given oral use of Zopiclone Tablets,while the observation group was given acupuncture based on the method of tonifying the kidney and soothing the liver. Both groups of patients were treated for consecutive 2 weeks. After 2 weeks of treatment,the clinical efficacy of the two groups was evaluated, and the changes in the traditional Chinese medicine(TCM)syndrome scores and the Pittsburgh Sleep Quality Index(PSQI)scores of the patients in the two groups were observed before and after treatment. The changes in the Hamilton Anxiety Scale(HAMA)-14 scores and Hamilton Depression Scale(HAMD)-17 scores were compared before and after treatment in the two groups. Results(1)The total effective rate of the observation group was 88.00%(22/25)and that of the control group was 76.00%(19/25). The efficacy of the observation group was slightly superior to that of the control group, but the difference was not statistically significant(P>0.05).(2)After treatment,the total TCM syndrome scores of the patients in the two groups were significantly improved(P<0.05), and the observation group was significantly superior to the control group in improving the total TCM syndrome scores, the difference being statistically significant(P<0.05).(3)After treatment,the PSQI scores and total scores of each item in the two groups were significantly improved(P<0.05),and the observation group was significantly superior to the control group in improving sleep efficiency and daytime dysfunction,the difference being statistically significant(P<0.05).(4)After treatment,the HAMA-14 score of the two groups were significantly improved(P<0.05),and the observation group was sig

关 键 词：针刺 补肾疏肝法 肾虚肝郁 围绝经期失眠 临床观察 

分 类 号：R246.9[医药卫生—针灸推拿学]