运动对儿童青少年不同生长阶段骨矿含量影响的Meta分析  

Effects of exercise on bone mineral content in children and adolescents at different growth stages:a Meta-analysis

作　　者：王燚 谌晓安[1] 张福兰[1] 周县委 徐涛 Wang Yi;Chen Xiaoan;Zhang Fulan;Zhou Xianwei;Xu Tao(College of Sports Science of Jishou University,Jishou 416000,China)

机构地区：[1]吉首大学体育科学学院,吉首416000

出　　处：《卫生研究》2023年第2期300-306,312,共8页Journal of Hygiene Research

基　　金：湖南省哲学社会科学基金(No.19YBA283);河南理工大学人文社会科学研究基金(No.SKND2023-20)。

摘　　要：目的评价运动对儿童青少年不同生长阶段骨矿含量(bone mineral content,BMC)的影响。方法计算机检索EMBASE、PubMed、Web of Science、中国知网、维普数据库、万方数据库,检索时限为数据库建立至2022年7月20日,以运动、儿童、青少年、BMC等相关词语为检索词,收集中、英文发表的关于运动对儿童青少年BMC影响的随机对照试验,运用Cochrane协作工具对纳入研究的质量进行评估,采用RevMan5.4软件进行Meta分析。选择标准化均数差(standard mean difference,SMD)及95%CI进行效应量合并。结果共纳入18篇文献(22项随机对照试验),1305例儿童青少年。Meta分析结果显示:与对照组相比,(1)运动能显著提升儿童青少年脊柱BMC(SMD=0.28,95%CI 0.17~0.40,P<0.01)和股骨颈BMC(SMD=0.40,95%CI 0.20~0.61,P<0.01),而对于全身BMC的影响无统计学意义(SMD=0.08,95%CI-0.04~0.21,P=0.19);(2)亚组分析可知,运动显著提升脊柱BMC的阶段为:青春期前(SMD=0.48,95%CI 0.27~0.69,P<0.01)和青春期早期(SMD=0.22,95%CI 0.05~0.39,P=0.01);运动显著提升股骨颈BMC的阶段为:青春期前(SMD=0.60,95%CI 0.05~1.16,P=0.03)、青春期早期(SMD=0.22,95%CI 0.01~0.43,P=0.04)和青春期中后期(SMD=0.43,95%CI 0.13~0.72,P<0.01)。结论运动对青春期前和青春期早期脊柱BMC以及整个儿童青少年时期股骨颈BMC都具有显著的提升作用,特别是在青春期前运动的效应量更高。OBJECTIVE To evaluate the effect of exercise on bone mineral content(BMC)in children and adolescents at different growth stages.METHODS EMBASE,PubMed,Web of Science,CNKI,VIP database and Wanfang database were searched.The randomized controlled trials(RCTS)published in Chinese and English on the effects of exercise on BMC in children and adolescents were collected using exercise,children,adolescents and BMC as search terms.Cochrane collaboration tool was used to evaluate the quality of the included studies,and RevMan5.4 software was used for Meta-analysis.The search time limit is from the establishment of the database to July 20,2022.RESULTS A total of 18 articles(22 RCTS)involving 1305 children and adolescents were included.The result of the Meta-analysis showed that:Compared with the control group,(1)exercise significantly improved spinal BMC(SMD=0.28,95%CI 0.17-0.40,P<0.01)and femoral neck BMC(SMD=0.40,95%CI 0.20-0.61,P<0.01),but not for systemic BMC(SMD=0.08,95%CI-0.04-0.21,P=0.19).(2)Subgroup analysis showed that exercise significantly improved spinal BMC in the following stages:prepubertal(SMD=0.48,95%CI 0.27-0.69,P<0.01)and early pubertal(SMD=0.22,95%CI 0.05-0.39,P=0.01).The stages in which exercise significantly improved femoral neck BMC were as follows:prepubertal(SMD=0.60,95%CI 0.05-1.16,P=0.03),early pubertal(SMD=0.22,95%CI 0.01-0.43,P=0.04),middle and late pubertal(SMD=0.43,95%CI 0.13-0.72,P<0.01).CONCLUSIONExercise significantly enhanced spinal BMC during preadolescence and early adolescence as well as femoral neck BMC throughout childhood and adolescence,especially with higher effect sizes during preadolescence.

关 键 词：运动 骨矿含量 儿童青少年 META分析 

分 类 号：R437.1[医药卫生—临床医学]