芳炔参与的三组分芳基化反应进展  

Recent Progress on Arylation with Aryne through Three-Component Reaction

作　　者：陈东平 杨春红 李明 赵国孝 王文鹏[1] 王喜存[1] 权正军[1] Chen Dongping;Yang Chunhong;Li Ming;Zhao Guoxiao;Wang Wenpeng;Wang Xicun;Quan Zhengjun(College of Chemistry and Chemical Engineering,Northwest Normal University,Lanzhou 730070)

机构地区：[1]西北师范大学化学化工学院,兰州730070

出　　处：《有机化学》2023年第2期503-525,共23页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.22061038,22067018);甘肃省自然科学基金(Nos.20YF3GA023,20JR5RA210)资助项目。

摘　　要：三组分反应具有操作简单、反应效率高等优势,契合“原子经济、绿色环保”等原则.目前,芳炔参与的无过渡金属催化的芳基化反应主要分为以下三种类型:(1)直接芳基化反应;(2)基于σ-键或π-键的芳炔插入反应;(3)芳炔参与的三组分反应.相比于发展较为成熟的直接芳基化反应和基于σ-键或π-键的芳炔插入反应,芳炔参与的三组分反应机理尚不清楚,相关的综述也较为少见.为了科研工作者方便查阅、了解芳炔参与的三组分反应,对近年来芳炔参与的芳基化三组分反应研究进展进行综述.The three component reaction has the advantages of simple operation and efficient reaction,in line with the principles of atomic economy and green environmental protection.At present,the arylation without transition metal catalyst is mainly divided into three types of as following:(1)the direct arylation,(2)the insertion of aryne intoσ-bond orπ-bond,and(3)the three-component reactions involving aryne.Compared with the direct arylation and the insertion of aryne intoσ-bond orπ-bond,the mechanism of three component reactions involving aryne is still unclear,and the published reviews are still lacking.In order to facilitate the scientific researchers to consult and understand the three-component reaction involved in aryne,the progresses in the three-component reaction involving aryne in recent years are reviewed.

关 键 词：芳炔 三组分反应 碳-杂原子 芳基化反应 

分 类 号：O621.25[理学—有机化学]