铜催化不饱和化合物硅加成反应的研究进展  

Recent Advances in Copper-Catalyzed Silyl Addition of Unsaturated Compounds

作　　者：韩彪 李维双 陈舒晗 张泽浪 赵雪 张瑶瑶 朱磊 Han Biao;Li Weishuang;Chen Shuhan;Zhang Zelang;Zhao;Xue;Zhang Yaoyao;Zhu Lei(School of Chemistry and Materials Science,Hubei Engineering University,Xiaogan,Hubei 432000;School of Materials Science and Engineering,Hubei University,Wuhan 430062)

机构地区：[1]湖北工程学院化学与材料科学学院,湖北孝感432000 [2]湖北大学材料科学与工程学院,武汉430062

出　　处：《有机化学》2023年第2期555-572,共18页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21774029,22108065);湖北省自然科学基金(No.2019CFB354);湖北省高等学校优秀中青年科技创新团队计划(No.T201816);孝感市自然科学计划(Nos.XGKJ2020010053,XGKJ2021010009)资助项目。

摘　　要：有机硅化合物不仅是十分有用的功能分子,而且是非常重要的有机合成中间体,在一定条件下通过适当的化学方法,可以转化为很多其它有用的功能性化合物.到目前为止,已经陆续发展了各种过渡金属参与的催化方法来制备有机硅化合物,其中铜催化不饱和化合物的硅加成反应是一种重要的合成有机硅化合物的方法.从不饱和化合物的种类出发,主要涉及α,β-不饱和化合物、亚胺、Morita-Baylis-Hillman(MBH)醇类化合物、对苯醌甲基化合物、α,β-不饱和炔羰化合物以及α,β-不饱和砜类化合物,综述了近几年在铜催化作用下这些不饱和化合物通过硅加成反应合成有机硅化合物的最新研究进展,有利于加深对铜催化硅加成反应的理解.Organosilicons are not only very useful functional molecules,but also important organic synthetic intermediates.It could be easily transformed into many other useful functional compounds under various conditions.So far,a lot of transition metal-catalyzed methods have been developed to prepare organosilicon compounds.Among them,copper-catalyzed silyl addition reactions to unsaturated compounds are extremely important for the synthesis of organosilicon compounds.Herein,the recent research progress in the synthesis of organosilicons by copper-catalyzed silyl addition of silyl reagents to diverse unsaturated compounds such asα,β-unsaturated carbonyl compounds,imines,Morita-Baylis-Hillman(MBH)alcohols,p-quinone methides,α,β-unsaturated alkyne carbonyl compounds andα,β-unsaturated sulfones is summarized.It will largely promote the development of such copper-catalyzed silyl addition reactions.

关 键 词：不饱和化合物 铜催化 硅加成 有机硅化合物 

分 类 号：O627.41[理学—有机化学]