放射生物学研究中物理剂量的规范化  

Dosimetry standardization in radiobiological research

作　　者：钱建军[1] 田野[1] 戴建荣 Qian Jianjun;Tian Ye;Dai Jianrong(Department of Radiotherapy and Oncology,the Second Affiliated Hospital of Soochow University,Institute of Radiotherapy and Oncology,Soochow University,Suzhou Key Laboratory of Radiotherapy and Oncology,Suzhou 215004,China;Department of Radiation Oncology,National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100021,China)

机构地区：[1]苏州大学附属第二医院放疗科/苏州大学放射肿瘤治疗学研究所/苏州市肿瘤放射治疗学重点实验室,苏州215004 [2]国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京100021

出　　处：《中华放射肿瘤学杂志》2023年第3期190-193,共4页Chinese Journal of Radiation Oncology

基　　金：苏州市放射治疗学临床医学中心项目(Szlcyxzx202103)。

摘　　要：科学研究结果的“再现性”问题目前已成为备受关注的焦点。放射生物学是研究电离辐射对活体组织生物效应的一门医学科学,也存在着严重的“再现性”问题,其中一个重要原因是物理剂量的不准确或缺乏剂量学报告的完整描述。剂量测定指南、规范与建议的使用,如物理剂量报告规范化评分系统,有助于提高放射生物学研究中物理剂量的规范性和准确性。本文对目前为改善放射生物学和放射物理学的合作、提高放射生物学研究中物理剂量规范性的各项指南和建议进行评议,为提高放射生物学研究的可再现性提供参考。In recent years,the issue of"reproducibility"of scientific research results has become more and more prominent.Radiobiology is a medical science that studies the biological effect of radiation on living organisms,and there is also a serious problem of"reproducibility of findings".Inaccuracy of physical dose or incomplete dosimetric reports is one of the main causes.Use of guidelines,specifications and recommendations for dosimetric measurement,such as the standardized scoring system for dosimetric reports,will help improving the standardization and accuracy of physical dose measurement in radiobiological research.In this article,multiple guidelines and recommends for improving collaboration between radiobiology and radiation physics,as well as for dose standardization of radiobiological research were evaluated,aiming to provide reference for improving the reproducibility of radiobiological research.

关 键 词：放射生物学 剂量学 物理剂量 规范化 可再现性 

分 类 号：R811.5[医药卫生—放射医学]