抗生素联合泪囊抽脓冲洗及泪道探通术治疗新生儿急性泪囊炎的效果观察  

Clinical effect of of neonatal acute dacryocystitis treated with antibiotics combined with lacrimal sac aspiration and lacrimal passage

作　　者：任艳红[1] 史彩平[1] 朱慧慧[1] 陆斌[1] REN Yanhong;SHI Caiping;ZHU Huihui;LU Bin(Department of Ophthalmology,Children’s Hospital,Zhejiang University School of Medicine,National Clinical Research CenterFor Child Health,Hangzhou,Zhejiang 310052,China)

机构地区：[1]浙江大学医学院附属儿童医院眼科<国家儿童健康与疾病临床医学研究中心>,浙江杭州310052

出　　处：《医药前沿》2023年第3期29-31,共3页Journal of Frontiers of Medicine

基　　金：浙江省教育厅应用研究基金资助项目(Y201839256)。

摘　　要：目的:观察抗生素联合泪囊抽脓冲洗及泪道探通术治疗新生儿急性泪囊炎的临床效果。方法:回顾性分析2016年1月—2022年7月在浙江大学医学院附属儿童医院眼科进行治疗的60例新生儿急性泪囊炎患儿的病例资料。患儿均在全身及局部应用抗生素控制感染的基础上行泪囊抽脓冲洗并行泪道探通术治疗,并取患儿泪囊脓液做一般细菌培养及药物敏感性检测。结果:一次手术治愈率89.39%,两次手术治愈率96.97%,多次手术治愈率100.00%。一般细菌培养阳性率64.29%,金黄色葡萄球菌、凝固酶阴性葡萄球菌及缓症链球菌占培养出菌种的67.50%。药敏结果显示多数病原体对头孢三代、左氧氟沙星及妥布霉素敏感。结论:抗生素联合泪囊抽脓冲洗并同次行泪道探通术是治疗新生儿急性泪囊炎的可行方案,临床经验性抗感染治疗首选头孢三代静滴,左氧氟沙星滴眼液或妥布霉素滴眼液滴眼治疗。Objective To explore the clinical efficacy of antibiotic combined with lacrimal sac drainage and probing of lacrimal passage at the same time in the treatment of neonatal acute dacryocystitis.Method A retrospective analysis was performed on the case data of 60 children with neonatal acute dacryocystitis treated in the Ophthalmology Department of Children’s Hospital of Zhejiang University School of Medicine from January 2016 to July 2022.On the basis of systemic and local application of antibiotics to control infection,the children were performed with drainage of lacrimal passage and probing of lacrimal passage at the same time,and their lacrimal sac pus was taken for general bacterial culture and drug sensitivity test.Results The success rate of one operation was 89.39%,the success rate of two operations was 96.97%,and the success rate of multiple operations was 100%.The positive rate of general bacterial culture was 64.29%.Staphylococcus aureus,Coagulase negative staphylococcus and Streptococcus mitis accounted for 67.50%of the cultured bacteria.Drug sensitivity results showed that most pathogens were sensitive to the third generation cephalosporin,levofloxacin and tobramycin.Conclusion Antibiotics combined with lacrimal sac aspiration and lacrimal passage probing at the same time is a feasible scheme to treat neonatal acute dacryocystitis.The first choice for clinical empirical anti infection treatment is intravenous drip of the third generation cephalosporin,and eye drops of levofloxacin or tobramycin.

关 键 词：新生儿 急性泪囊炎 泪道探通 

分 类 号：R722.1[医药卫生—儿科]