浙江省台州市解脲支原体、沙眼支原体和淋球菌感染情况分析  

Analysis of Ureaplasma urealyticum,Chlamydia trachomatis,and Neisseria gonorrhoeae infection in Taizhou City,Zhejiang Province

作　　者：孙彤 王冬莲 陈微 陈佳喜[1,2] 劳建萍 SUN Tong;WANG Dong-lian;CHEN Wei;CHEN Jia-xi;LAO Jian-ping(Taizhou Hospital,Zhejiang 317000,China;不详)

机构地区：[1]浙江省台州医院,浙江317000 [2]台州恩泽医疗中心(集团)恩泽医院

出　　处：《中国卫生检验杂志》2023年第5期543-546,共4页Chinese Journal of Health Laboratory Technology

基　　金：浙江省公益性技术应用研究(LGF20H200006)。

摘　　要：目的 分析浙江省台州市就诊患者解脲支原体(UU)、沙眼支原体(CT)和淋病奈瑟菌(NG)的感染情况。方法 应用实时荧光定量PCR方法对台州地区56 069例患者生殖道、尿道分泌物或尿液标本进行UU、CT和NG检测。结果 UU、CT、NG阳性率分别为50.24%、7.77%和7.25%,16岁~24岁的阳性率较高,女性UU阳性率高于男性,而CT和NG男性阳性率高于女性,差异均有统计学意义(P<0.05)。男女UU、CT和NG阳性和阴性的平均年龄差异有统计学意义(P<0.001)。男女混合感染主要以UU+CT为主,UU+NG次之。2016年—2021年阳性率整体虽有所下降,但UU在2021年有所反弹。UU、CT夏秋季检出率低,春冬季检出率稍高,NG夏秋季检出率稍高,春冬季检出率较低。结论 台州地区UU、CT、NG阳性率较高,尤其在青壮年中阳性率较高,季节、年龄和性别都是干扰因素。对于有临床表现的患者应进行联合检测,以达到最佳的治疗效果。Objective This paper aims to analyze the infection of Ureaplasma urealyticum(UU), Chlamydia trachomatis(CT), and Neisseria gonorrhoeae(NG) in patients in Taizhou City, Zhejiang Province. Methods Real-time quantitative PCR was used to detect UU, CT and NG of genital tract and urethra secretions or urine samples from 56 069 patients in Taizhou area. Results The positive rates of UU, CT, and NG were 50.24%, 7.77%, and 7.25%, respectively, with a higher rate of positivity in 16-24 years old, and a higher positive rate of UU in females than in males, while the positive rates of CT and NG in males were higher than that in females, and the differences were statistically significant(P<0.05). The mean age differences of positive and negative UU, CT, and NG between male and female were statistically significant(P<0.001). UU+CT was the dominant mixed infection to male and female, followed by UU+NG. Although the overall positive rate decreased from 2016 to 2021, UU rebounded in 2021. The detection rate of UU and CT was low in summer and autumn, but slightly higher in spring and winter. The detection rate of NG was slightly higher in summer and autumn, but low in spring and winter. Conclusion The positive rates of UU, CT, and NG are high in Taizhou, especially among young adults, and season, age and gender are all confounding factors. Combined testing should be performed for patients with clinical manifestations to achieve the best treatment effect.

关 键 词：解脲支原体 沙眼支原体 淋球菌 

分 类 号：R446.5[医药卫生—诊断学]