某地母乳中17种元素含量及其影响因素研究  

A study on the contents of 17 elements and influential factors in breast milk from an area of China

作　　者：罗亚翠 何霞 张海君[2] 方家阳 张海蕾[2] 汤鋆[3] LUO Ya-cui;HE Xia;ZHANG Hai-jun;FANG Jia-yang;ZHANG Hai-lei;TANG Jun(Department of Physics and Chemistry,Taizhou Municipal Center for Disease Ccontrol and Prevention,Zhejiang 318000,China;不详)

机构地区：[1]台州市疾病预防控制中心理化科,浙江318000 [2]台州市疾病预防控制中心 [3]浙江省疾病预防控制中心

出　　处：《中国卫生检验杂志》2023年第5期616-623,共8页Chinese Journal of Health Laboratory Technology

基　　金：台州市科技局项目(1902ky91)。

摘　　要：目的 研究某地母乳中17种元素的含量及其影响因素。方法 随机选取某地2所大型医院生产的产妇75例,其中暴露组45例(居住地曾为电子垃圾拆解地),对照组30例(居住地为非电子垃圾拆解地),收集其产后母乳,采用电感耦合等离子体质谱法测定其中的17种元素,并对产妇进行问卷调查。结果 2组产妇人口学特征差异无统计学意义(P>0.05);暴露组产妇母乳中Zn、Mn含量高于对照组,差异有统计学意义(P<0.05)。广义线性回归分析显示年龄、分娩方式、文化程度、家庭收入、纯母乳是影响母乳元素含量的主要因素,暴露组母乳还受到职业、产后天数、粮食来源和接触电子垃圾的影响,对照组则受被动吸烟和蔬菜来源的影响。结论 暴露组产妇存在一定的Zn、Mn暴露风险,母乳中元素含量受多种因素影响,应制定相应措施降低母婴健康风险。Objective This paper aims to investigate the contents and influential factors of 17 elements in breast milk from an area of China. Methods A total of 75 women were randomly selected from two major hospitals in this local area, including 45 women as the exposed group(living in the former e-waste recycling area) and 30 women as the control group(living in the non-e-waste recycling area). The breast milk were collected after delivery and the questionnaires were completed by the selected women. The contents of 17 element in breast milk were determined by inductively coupled plasma mass spectrometry(ICP-MS). Results There was no statistical significance on the difference in demographic characteristics between the two groups(P>0.05). The levels of Zn and Mn in breast milk of the exposed group were higher than those of the control group, with the difference statistically significant(P<0.05). Generalized linear model regression showed that delivery mode, maternal age, education, family income, and breast-feeding were the main factors influencing element levels in breast milk. Besides, maternal occupation, postpartum days, source of grain, and e-waste contact had significant effects on element levels of breast milk from the exposed group, while passive smoking and source of vegetables had significant effects on breast milk from the control group. Conclusion Women from the exposed group were at risk of exposure to Zn and Mn. Many factors have relationship with element levels in breast milk. Corresponding measures should be conducted to reduce the health risk for mothers and infants.

关 键 词：产妇 母乳 元素 电子垃圾 

分 类 号：R174*.4[医药卫生—妇幼卫生保健]