聚多巴胺/聚乳酸涂层改性硅酸钙陶瓷支架的性能研究  

Study on the Properties of Calcium Silicate Ceramic Scaffold Modified by Polydopamine/polylactic Acid Coating

作　　者：王桂森 WANG Guise(Department of Mechanical Engineering,Hebei University of Science and Technology,Shijiazhuang 050018,China)

机构地区：[1]河北科技大学机械工程学院,河北石家庄050018

出　　处：《电加工与模具》2023年第S01期50-54,共5页Electromachining & Mould

摘　　要：3D打印多孔生物活性陶瓷支架具有良好的促进血管化骨再生的能力,但是力学性能比较差,限制了在临床上的应用。为了提高支架的力学性能与亲水性,将3D打印的硅酸钙支架依次浸入到含有聚乳酸的溶液和含有聚多巴胺的溶液中,得到聚多巴胺/聚乳酸硅酸钙复合陶瓷支架。通过在硅酸钙支架表面覆盖聚多巴胺/聚乳酸涂层,支架孔壁表面的微孔被涂层覆盖,并使孔壁变得平坦、光滑。经验证,这是一种提高支架的力学性能并使支架获得亲水性的有效方法。Porous bioactive ceramic scaffold by 3D printing has good ability to promote vascularized bone regeneration,but its poor mechanical property limits its clinical application.In order to improve the hydrophilicity and mechanical properties of the scaffold,the 3D printed calcium silicate scaffold was successively immersed into the solution containing polylactic acid and the solution containing polydopamine to obtain the polydopamine/polylactic acid modified calcium silicate composite ceramic scaffold.By covering the surface of calcium silicate scaffold with polydopamine and polylactic acid coating,the micropores on the surface of the scaffold are covered with the coating,and the pore wall becomes flat and smooth.The result showed that this is an effective method to improve the mechanical properties of the scaffold and make it hydrophilic.

关 键 词：3D打印 硅酸钙 亲水性 力学性能 

分 类 号：TG669[金属学及工艺—金属切削加工及机床]