白虎加人参汤加减联合耳穴压豆治疗2型糖尿病肺胃热盛证临床观察  

Clinical Observation of Modified White Tiger Decoction plus Ginseng Combined with Auricular Point Pressing with Beans in the Treatment of Type 2 Diabetes Mellitus with Syndrome of Excessive Lung-Stomach Heat

作　　者：杨鑫培 YANG Xin-pei(Xuchang Hospital of Traditional Chinese Medicine,Xuchang,Henan,China,461000)

机构地区：[1]许昌中医院,河南许昌461000

出　　处：《河南中医》2023年第4期504-508,共5页Henan Traditional Chinese Medicine

基　　金：河南省中医药科学研究专项课题项目(2020ZY3016)。

摘　　要：目的:观察白虎加人参汤加减联合耳穴压豆治疗2型糖尿病(diabetes mellitus type 2,T2DM)肺胃热盛证的临床疗效。方法:选取2021年8月至2022年8月许昌中医院内分泌科收治的T2DM患者80例,按照随机数字表法分为治疗组和对照组,每组各40例。对照组给予盐酸二甲双胍缓释片治疗,治疗组在对照组治疗的基础上给予白虎加人参汤联合耳穴压豆治疗。观察两组患者的临床疗效、不良反应,比较两组治疗前后糖脂代谢指标[空腹血糖(fasting blood glucose, FBG)、餐后2h血糖(2 hours postprandial blood glucose, 2 hPG)、糖化血红蛋白(glycosylated hemoglobin, HbA1c)、总胆固醇(total cholesterol, TC)、三酰甘油(three acyl glycerin, TG)]和胰岛素抵抗指标水平变化情况。结果:对照组有效率为80.00%,治疗组有效率为95.00%,治疗组有效率高于对照组,差异有统计学意义(P<0.05);治疗组治疗后FPG、2 hPG以及HbA1c等糖代谢指标和TC、TG等脂代谢指标水平均低于对照组,差异有统计学意义(P<0.05);治疗组治疗后空腹胰岛素、空腹胰岛素抵抗指数低于对照组,差异有统计学意义(P<0.05);对照组不良反应发生率为20.00%,治疗组不良反应发生率为5.00%,治疗组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论:白虎加人参汤加减联合耳穴压豆治疗T2DM肺胃热盛证能够提高临床疗效,减少不良反应,调节糖脂代谢紊乱,有效缓解胰岛素抵抗。Objective:To observe the clinical efficacy of Modified White Tiger Decoction plus Ginseng combined with auricular point pressing with beans on type 2 diabetes mellitus(T2DM)with syndrome of excessive lung-stomach heat.Methods:A total of 80 T2DM patients admitted to The Endocrinology Department of Xuchang Hospital of Traditional Chinese Medicine from August 2021 to August 2022 were selected and randomly divided into the treatment group and the control group,with 40 cases in each group.The control group was treated with Metformin Hydrochloride Tablets,while the treatment group was treated with White Tiger Decoction plus Ginseng combined with auricular point pressing with beans on the basis of the control group.The clinical efficacy and adverse reactions of the two groups were observed.The changes of glucose and lipid metabolism indicators including fasting blood glucose(FBG),2 hours postprandial blood glucose(2 hPG),glycated hemoglobin(HbAlc),total cholesterol(TC),three acyl glycerol(TG),and insulin resistance indicators before and after treatment of the two groups were compared.Results:The ef fective rate of the control group was 80.00%,while that of the treatment group was 95.00%.The effective rate of the treatment group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of glucose metabolism indicators such as FPG,2 hPG,HbAlc,and lipid metabolism indicators such as TC and TG in the treatment group were lower than those in the control group,and all the differences were statistically significant(P<0.05);The fasting insulin and fasting insulin resistance index in the treatment group were significantly lower than those in the control group,and all the differences were statistically significant(P<0.05).The incidence of adverse reactions in the control group was 20.00%,while that in the treatment group was 5.00%.The incidence of adverse reactions in the treatment group was lower than that in the control group,and the difference was statisticall

关 键 词：2型糖尿病 肺胃热盛证 白虎加人参汤 耳穴压豆 《伤寒论》 张仲景 

分 类 号：R259.871[医药卫生—中西医结合]