出 处:《中国实用医药》2023年第7期141-144,共4页China Practical Medicine
基 金:广西区卫生健康委自筹课题(项目编号:Z20191062)。
摘 要:目的分析配偶焦虑、抑郁状况与帕金森病患者生存质量的相关性。方法45例帕金森病且配偶健在的患者,利用欧洲癌症研究和生活质量综合评定问卷-74(成人用)(GQOL-74)、焦虑自评量表(SAS)、抑郁自评量表(SDS)对患者及其配偶的生存质量及焦虑、抑郁状况进行分析,按照患者配偶焦虑、抑郁程度分成无焦虑-抑郁组(16例)、轻度组(12例)、中度组(10例)、重度组(7例)。专科及心理医生对帕金森病配偶进行为期6个月的心理干预后,再次使用量表对各组患者及其配偶分别进行生存质量,焦虑、抑郁状况评估,分析患者配偶焦虑、抑郁状况与患者生存质量的相关性。结果干预后,无焦虑-抑郁组及重度组患者配偶SAS和SDS评分与干预前比较差异无统计学意义(P>0.05);轻度组、中度组患者配偶SAS评分分别为(48.29±4.52)、(62.81±5.92)分,SDS评分分别为(45.78±5.13)、(61.57±7.01)分,明显低于本组干预前的(54.34±6.21)、(69.24±5.78)、(53.04±7.35)、(68.43±7.29)分,差异有统计学意义(P<0.05)。干预后,无焦虑-抑郁组、轻度组及中度组患者生存质量评分分别为(85.24±8.12)、(85.11±6.32)、(82.34±4.53)分,明显高于本组干预前的(76.15±7.16)、(77.72±9.21)、(75.92±6.27)分,差异有统计学意义(P<0.05);重度组患者生存质量评分与干预前比较差异无统计学意义(P>0.05)。相关分析提示,患者配偶SAS和SDS得分与患者生活质量综合评定问卷评分呈负相关(r=-0.45、-0.53,P<0.05)。结论对存在轻、中度焦虑、抑郁的帕金森病患者配偶进行心理干预,能够有效减少其不良情绪,缓解焦虑、抑郁心理,提升患者及配偶的认知能力,增进患者与配偶之间情感,提高帕金森病患者生存质量。Objective To analyze the correlation of spouse anxiety and depression status with quality of life in patients with Parkinson's disease.Methods 45 patients with Parkinson's disease and surviving spouses were analyzed for quality of life and anxiety and depression status of patients and their spouses using the Generic Quality of Life Inventory-74(for adults)(GQOL-74),the Self-Rating Anxiety Scale(SAS),and the Self-Rating Depression Scale(SDS).According to the degree of anxiety and depression of the patients'spouses,they were divided into anxiety-depression free group(16 cases),mild group group(12 cases),moderate group(10 cases),and severe group(7 cases).After 6 months of psychological intervention for the spouses of patients with Parkinson's disease,specialists and psychologists used the scale again to evaluate the quality of life,anxiety and depression of patients and their spouses,respectively,and the correlation between the anxiety and depression status of patients'spouses and the quality of life of patients.Results After intervention,the differences in SAS and SDS scores of spouses in the anxiety-depression free group and the severe group were not statistically significant compared with those before intervention(P>0.05).The SAS scores of spouses in mild group and moderate group were(48.29±4.52)and(62.81±5.92)points,and the SDS scores were(45.78±5.13)and(61.57±7.01)points,which were significantly lower than those of(54.34±6.21),(69.24±5.78)point and(53.04±7.35),(68.43±7.29)points before intervention,and the differences were statistically significant(P<0.05).After intervention,the quality of life scores in the anxiety-depression free group,the mild group and the moderate group were(85.24±8.12),(85.11±6.32)and(82.34±4.53)points,which were significantly higher than those of(76.15±7.16),(77.72±9.21)and(75.92±6.27)points before intervention,and the differences were statistically significant(P<0.05).After intervention,the difference in quality of life score of the severe group was not statistically signi
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