参芎葡萄糖注射液安全性风险分析与思考  

Security risk of Shenxiong glucose injection

作　　者：杨洋 杨红玉 杨月明 金丹 YANG Yang;YANG Hongyu;YANG Yueming;JIN Dan(Liaoning Center for Drug Evaluation and Inspection,Shenyang,Liaoning 110036,China)

机构地区：[1]辽宁省药品审评查验中心,辽宁沈阳110036

出　　处：《安徽医药》2023年第5期1057-1060,共4页Anhui Medical and Pharmaceutical Journal

摘　　要：目的 分析参芎葡萄糖注射液致药品不良反应(ADR)发生的特点及风险因素,为临床安全用药提供参考。方法 对辽宁省内药品不良反应监测数据、国内文献参芎葡萄糖注射液相关不良反应进行整理与分析。结果 参芎葡萄糖注射液在临床使用过程中可能引起皮疹、瘙痒、头晕、头痛、恶心、胸闷、心悸、潮红、呼吸困难、呕吐、寒战、发热、过敏样反应、血压升高、过敏性休克等不良反应。结论 药品上市许可持有人应及时完善产品说明书中安全性提示信息,加强临床用药安全宣传,以保证公众用药安全。Objective To analyze the characteristics of and risk factors for adverse drug reactions(ADRs) caused by Shenxiong glucose injection,and to provide reference for medication safety in clinical practice.Methods The monitoring data of drug ADRs in Liaoning province and related ADRs report of Shenxiong glucose injection in domestic literature were collated and analyzed.Results Shenxiong glucose injection may cause rash,itching,dizziness,headache,nausea,chest tightness,palpitations,flushing,dyspnea,vomiting,chills,fever,anaphylactic reaction,elevated blood pressure,anaphylactic shock and other adverse reactions during clinical use.Conclusion The drug marketing authorization holders should improve the safety information in drug specifications in time and strengthen the publicity of clinical drug use safety to ensure public safety in drug use.

关 键 词：药物相关性副作用和不良反应 植物制剂 参芎葡萄糖注射液 安全性 说明书 

分 类 号：R969[医药卫生—药理学]