贝类性别决定与分化相关基因研究进展  

Research advances in genes related to sex determination and differentiation in molluscs

作　　者：于红[1,2] 郭浪 李琪 YU Hong;GUO Lang;LI Qi(Key Laboratory of Mariculture,Ocean University of China,Ministry of Education,Qingdao 266003,China;Laboratory for Marine Fisheries Science and Food Production Processes,Qingdao National Laboratory for Marine Science and Technology,Qingdao 266237,China)

机构地区：[1]中国海洋大学,海水养殖教育部重点实验室,山东青岛266003 [2]青岛海洋科学与技术国家实验室,海洋渔业科学与食物产出过程功能实验室,山东青岛266237

出　　处：《水产学报》2023年第3期12-26,共15页Journal of Fisheries of China

基　　金：国家重点研发计划(2018YFD0900200)。

摘　　要：性别决定与分化是生命发育的基本事件,性别决定与分化机制一直是生命科学研究的热点问题。贝类具有雌雄同体、雌雄异体、雄性先熟和性转换等复杂的性别类型,是研究无脊椎动物性别决定与分化机制及其演化进程的理想动物类群。挖掘贝类性别决定与分化调控基因,阐明相关基因的调控作用,对于揭示贝类性别决定与分化的分子机制具有重要意义。本文就贝类性别决定与分化相关基因的研究进展进行了综述,并对该研究领域进行展望,以期为贝类的性别决定和分化机制、生殖操作和遗传改良等研究提供参考。Sex determination and differentiation are basic events of development and key processes of sexual reproduction.The mechanism of sex determination and differentiation is both baffling and intriguing.Mollusca is the second largest animal phylum,harboring diverse sexual systems including hermaphroditism,gonochorism,protandry and sex reversal.Therefore,molluscs are an ideal animal group to study the mechanisms of sex determination and differentiation.Although efforts towards understanding sex determination and differentiation of molluscs can be traced back to the 1940s,the mechanisms of sex determination and differentiation of molluscs remain enigmatic.Solving the riddle of sex determination and differentiation and identifying key genes would help us better understand the biology of molluscs and provide insights into sexual evolution in the animal kingdom.Here we review the research progress and the prospects of sex determination and sex related genes such as Dmrt,Foxl2,Sox,Wnt4,Dax1,β-catenin,Fem-1,Vasa,Nanos and GnRH in molluscs.We also propose several goals about mechanistic underpinning of sex determination in molluscs which require further study.

关 键 词：贝类 性别决定 性别分化 基因 

分 类 号：Q789[生物学—分子生物学] S917.4[农业科学—水产科学]