慢性应激与心血管疾病的研究现状  

Research status of chronic stress and cardiovascular disease

作　　者：陈焱 陈胜岳 吕志博 徐清 卢川 郑铭鑫 赵昕[1] Chen Yan;Chen Sheng-yue;LüZhi-bo;Xu Qing;Lu Chuan;Zheng Ming-xin;Zhao Xin(The Second hospital of Dalian Medicial University,Dalian,Liaoning 116023,China;Neusoft Research of Intelligent Healthcare Technology,Co.Ltd,Shenyang,Liaoning 110170,China)

机构地区：[1]大连医科大学附属第二医院心血管内科,辽宁大连116023 [2]沈阳东软智能医疗科技研究院有限公司,辽宁沈阳110170

出　　处：《中国现代医学杂志》2023年第7期55-59,共5页China Journal of Modern Medicine

基　　金：科技部国家重点研发计划(No:2020YFC2004701);2022年辽宁省“揭榜挂帅”科技计划(重大)项目(No:2022JH1/10400004)。

摘　　要：人体在急性应激状态下,某些激素水平急剧升高,进而导致心血管事件的风险显著增加。而慢性应激所引起的不良后果表现得相对迟滞,并非像急性应激那样以即刻的临床不良事件引人注目。值得注意的是,近年来慢性应激被证明会导致更为严重的机体炎症反应与动脉粥样硬化,因此作为心血管不良事件的危险因素也备受关注。该文综述慢性应激与心血管疾病的研究现状。Acute stress can lead to a dramatic increase in levels of certain hormones in the human body,which in turn leads to a significant increase in the risk of cardiovascular events.The adverse consequences caused by chronic stress are always relatively delayed,and immediate clinical adverse events are not as striking as acute stress.However,it is worth noting that chronic stress has been shown to lead to more severe body inflammatory response and atherosclerosis in recent years,so it has also attracted much attention as a risk factor for cardiovascular adverse events.This article reviews the current research status of chronic stress and cardiovascular disease.

关 键 词：心血管疾病 慢性应激 动脉粥样硬化 下丘脑-垂体-肾上腺轴 减压疗法 

分 类 号：R54[医药卫生—心血管疾病]