1819例神经内科缺血性脑卒中住院患者用药情况分析与合理性评价  

Analysis and Rationality Evaluation of Drug Use in 1819 Inpatients with Ischemic Stroke in Neurology Department

作　　者：付虹 戎有和[2] 王雨昕 FU Hong;RONG Youhe;WANG Yuxin(Dept.of Pharmacy,Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China;College of Nursing,Nanjing University of Traditional Chinese Medicine,Nanjing 210029,China;College of Kangda,Nanjing Medical University,Nanjing 210029,China)

机构地区：[1]南京中医药大学附属医院药学部,南京210029 [2]南京中医药大学护理学院,南京210029 [3]南京医科大学康达学院,南京210029

出　　处：《中国医院用药评价与分析》2023年第3期357-360,366,共5页Evaluation and Analysis of Drug-use in Hospitals of China

基　　金：江苏省药学会-奥赛康临床药学基金科研项目(No.A201902);江苏省中医院面上科研项目(No.Y200220)。

摘　　要：目的:了解江苏省中医院(以下简称“该院”)神经内科缺血性脑卒中住院患者用药的基本情况和合理性,为临床治疗药物的合理选择提供参考。方法:采用回顾性调查方法,将2021年该院神经内科诊断为缺血性脑卒中的1 819例住院患者作为研究对象,分析其用药的基本情况;基于药物利用评价(DUR)方法,以限定日剂量和药物利用指数(DUI)为指标,评价缺血性脑卒中患者药物治疗的合理性。结果:1 819例患者中,男性患者居多,为1 050例(占57.72%);患者平均年龄为(68.86±11.98)岁;单药抗血小板治疗的患者有995例(占54.70%),双联抗血小板治疗的患者有609例(占33.48%)。单药降脂治疗中选用最多的药品为阿托伐他汀(555例,占30.51%),联合降脂治疗中选用最多的为阿托伐他汀联合依折麦布(885例,占48.65%)。使用中药注射剂的患者共1 088例,占59.81%。DUR法统计结果显示,DUI>1的药品有9种,DUI<1的药品有10种,DUI=1的药品有25种。结论:采用DUR法可以从不同角度评价药物在临床中的使用特点和基本规律,进一步规范临床用药。OBJECTIVE:To investigate the current status and rationality of drug use in inpatients with ischemic stroke in the neurology department of Jiangsu Province Hospital of Chinese Medicine(hereinafter referred to as“the hospital”),so as to provide reference for the rational selection of clinical therapy drugs.METHODS:Retrospective survey method was used,1819 inpatients diagnosed with ischemic stroke in the neurology department of the hospital in 2021 were used as study subjects to analyze the basic situation of medication.The rationality of drug therapy in patients with ischemic stroke was evaluated based on the drug utilization review(DUR)method,with the defined daily dose and drug utilization index(DUI)as indicators.RESULTS:Among the 1819 patients,1050 were males,accounting for 57.72%.The average age of the patients was(68.86±11.98)years.Patients treated with single antiplatelet therapy and double antiplatelet therapy were respectively 995 cases(54.70%)and 609 cases(33.84%).Atorvastatin(555 cases,30.51%)was the most used single lipid-lowering therapy drugs,and atorvastatin combined with ezetimibe(885 cases,48.65%)was the most used combined lipid-lowering therapy drugs.A total of 1088 patients used traditional Chinese medicine injection,accounting for 59.81%.According to the DUR method,there were 9 kinds of DUI>1,10 kinds of DUI<1 and 25 kinds of DUI=1.CONCLUSIONS:DUR method can be used to evaluate the characteristics and basic rules of drug use in clinic from different perspectives,which promote the clinical treatment more rationally.

关 键 词：缺血性脑卒中 合理性 药物利用指数 药物利用评价 

分 类 号：R969.3[医药卫生—药理学]