纳米生物材料及其表面对成骨细胞生物学行为影响的研究进展  

Research progress of the effects of nano-biomaterials and their surfaces on the biological behavior of osteoblast cells

作　　者：王一席 艾克清颜 葛张洁 高彦峰 董跟喜[3] 张瑞[3] Wang Yixi;Ai Keqingyan;Ge Zhangjie;Gao Yanfeng;Dong Genxi;Zhang Rui(The Second Hospital of Lanzhou University,Lanzhou Gansu,730000;Liuzhou People's Hospital,Liuzhou Guangxi,545000;Lanzhou University Stomatological Hospital,Lanzhou Gansu,730000;Lanzhou Chengguan Maternal and Child Health Care Hospital,Lanzhou Gansu,730000,China)

机构地区：[1]兰州大学第二医院,甘肃兰州730000 [2]柳州市人民医院,广西柳州545000 [3]兰州大学口腔医院,甘肃兰州730000 [4]兰州市城关区妇幼保健院,甘肃兰州730000

出　　处：《生物骨科材料与临床研究》2023年第2期81-85,90,共6页Orthopaedic Biomechanics Materials and Clinical Study

基　　金：兰州市科技局计划项目(2018-3-61)。

摘　　要：骨组织工程是再生医学的重要组成部分,支架材料和种子细胞是其关键。近年来,随着纳米技术等相关学科的发展,在骨组织工程领域,研究人员对成骨细胞株的选择和培养、纳米材料的元素组成、表面形态、表面粗糙度及表面改性等方面进行了大量研究,并在纳米材料对成骨细胞生物学行为的影响方面取得了重要的研究成果和进展,本文对近年来在该领域内的研究进展作一综述。Bone tissue engineering is an important component of regenerative medicine,for which scaffold materials and seed cells are key points.In recent years,with the development of nanotechnology and other related disciplines,researchers in the field of bone tissue engineering have conducted a lot of research on the selection and culture of osteoblast cell lines,elemental composition of nanomaterials,surface morphology,surface roughness and surface modification,and have made important research findings and progress in the effects of nanomaterials on the biological behavior of osteoblasts.This paper presents a review of the recent research progress in this field.

关 键 词：骨组织工程 成骨细胞 纳米生物材料 生物学行为 

分 类 号：R318.08[医药卫生—生物医学工程]