原位电化学与核磁共振联用新技术及其应用进展  

A New Hyphenated Technique of in Situ Electrochemical NMR and the Application Progress

作　　者：张晓萍 张思月 汪明畅 张钰桐 苗莎菻 王瑜 孙伟[1] ZHANG Xiao-Ping;ZHANG Si-Yue;WANG Ming-Chang;ZHANG Yu-Tong;MIAO Sha-Lin;WANG Yu;SUN Wei(College of Chemistry and Chemical Engineering,Key Lab of Functional Materials and Photoelectrochemistry of Haikou,Hainan Normal University,Haikou 571158,China)

机构地区：[1]海南师范大学化学与化工学院,海口市功能材料与光电化学重点实验室,海口571158

出　　处：《应用化学》2023年第3期317-328,共12页Chinese Journal of Applied Chemistry

基　　金：国家自然科学基金青年科学基金项目(No.22102043);海南省自然科学基金高层次人才项目(Nos.220RC594)资助。

摘　　要：电极表面微观的电化学反应动力学机制无法通过孤立的传统电化学方法直接揭示,核磁共振技术能在分子水平上提供待测样品的化学位移和J耦合产生的微小分裂等信息,它可以更容易地鉴定同分异构体、分子构象和电子变化。因此,原位电化学与核磁共振联用技术可以从分子层面上对物质反应机理和反应动力学过程进行原位无损实时研究,发现非原位技术无法监测的短寿命中间体,揭示反应机理和构效关系等相关信息,是一种非常有发展前途的原位谱学技术。但是由于电化学池和核磁共振的不兼容性,对原位电化学与核磁共振的研究及应用相对较少,为了让更多的人了解原位电化学与核磁共振联用这一新技术,文章分别阐述了该技术的国内外进展、工作原理、面临的挑战及其在电化学催化及物质反应机理、燃料电池和药物研究等方面的应用,并对今后需要解决的关键性问题进行了展望。The microscopically dynamic mechanism of electrochemical reaction on electrode-surfaces fails to uncover by isolated traditional electrochemical method.Nuclear magnetic resonance(NMR)technology provides the message of sample's chemical shift and the tiny split produced by J coupling at a molecular level,it can be easier to identify isomer,molecular construct and electronic change.Hence,in situ electrochemical NMR hyphenated technique(EC-NMR technique)permits to monitor the reaction pathway and dynamic mechanism of the electrochemical reactions nondestructively at a molecular level.It seems to be more performing technique to reveal the reaction mechanism,structure-function relationship,and to discover unstable chemical intermediates which the ex-situ technique will never be.However,for the incompatibility between electrochemical cells and NMR,the study and application of the in situ EC-NMR technique is relatively lack.In order to understand the new technique for much more people,the article explains the development aboard and at home of the EC-NMR technology,working principle,challenge,and application which in electrochemical catalysis,the reaction mechanisms,fuel cell,and medication research.Future key issues of EC-NMR technology are also predicted.

关 键 词：原位电化学池 核磁共振 电化学-核磁共振联用技术 

分 类 号：O652.7[理学—分析化学]