三焦针法调控脑-肠-微生物轴治疗阿尔茨海默病的研究进展  

Research progress in the treatment of Alzheimer's disease by regulating brain-gut-microbiome axis with"Sanjiao"acupuncture method

作　　者：李虹 闫隆 钱玉林 于涛[1] 丛珊 王煜 韩景献[3] 王猛 Li Hong;Yan Long;Qian Yulin;Yu Tao;Cong Shan;Wang Yu;Han Jingxian;Wang Meng(Department of Comprehensive Rehabilitation,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine National Clinical Trial Center for Acupuncture and Moxibustion,Tianjin 300193,China;Acupuncture Department,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;Acupuncture Research Institute,First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China;Graduate School of Tianjin University of Traditional Chinese Medicine,Tianjin 301617,China)

机构地区：[1]天津中医药大学第一附属医院综合康复科国家中医针灸临床医学研究中心,天津300193 [2]天津中医药大学第一附属医院针灸科,天津300193 [3]天津中医药大学第一附属医院针灸研究所,天津300193 [4]天津中医药大学研究生院,天津301617

出　　处：《中华老年医学杂志》2023年第4期484-488,共5页Chinese Journal of Geriatrics

基　　金：国家自然科学基金(81704148)。

摘　　要：近年研究发现脑-肠-微生物轴(BGMA)与阿尔茨海默病(AD)的发生发展息息相关,BGMA能够在神经-免疫、肠道微生物群等多方面影响AD,是治疗AD的潜在新靶点。三焦针法是全国名中医韩景献教授依据其提出的"三焦气化失司-衰老"理论所创立,在临床被广泛运用于AD等老年性疾病的治疗。本文就三焦理论及三焦针法与BGMA的联系做一综述,以期在未来三焦针法调控BGMA能够成为治疗AD的新靶点。Recent studies have found that the brain-gut-microbiome axis(BGMA)is closely related to the occurrence and development of Alzheimer's disease(AD).BGMA can affect AD in various aspects such as neuro-immune regulation and intestinal microflora,and is a potential new target for the treatment of AD.The"Sanjiao"acupuncture method is proposed by professor Han Jingxian,a famous Chinese medicine practitioner,based on his theory of"dysfunction of Qi activity of Sanjiao leads to aging",and has been widely used in the treatment of AD and other age-related diseases in clinical practice.This article reviews the theory of"dysfunction of Qi activity of Sanjiao leads to aging"and the relationship between the"Sanjiao"acupuncture method and BGMA,with the hope that the"San Jiao"acupuncture method can become a new target for treatment of AD in the future.

关 键 词：三焦 阿尔茨海默病 脑-肠-微生物轴 

分 类 号：R246.6[医药卫生—针灸推拿学]