经食管实时三维超声心动图评价房颤患者左心耳功能及其与血栓形成的相关性  

Evaluation of Left Atrial Appendage Function and Its Correlation with Thrombosis in Patients with Atrial Fibrillation by Transesophageal Real-time Three-dimensional Echocardiography

作　　者：赵志先 刘宇 ZHAO Zhixian;LIU Yu(The Second Affiliated Hospital of Baotou Medical College of Inner Mongolia University of Science and Technology,Baotou 014030,China)

机构地区：[1]内蒙古科技大学包头医学院第二附属医院,内蒙古包头014030

出　　处：《中国医学创新》2023年第11期104-107,共4页Medical Innovation of China

摘　　要：目的:探讨与分析经食管实时三维超声心动图评价房颤患者左心耳(LAA)功能及其与血栓形成的相关性。方法:选择2021年1月1日-2022年8月1日在内蒙古科技大学包头医学院第二附属医院诊治的60例房颤患者作为研究对象,所有患者均给予经食管实时三维超声心动图检查,观察LAA功能,判断血栓形成情况,并对血栓形成与LAA功能进行相关性分析。结果:60例患者中,发生血栓10例,占比16.67%。血栓组房颤类型、体重指数、年龄、病程、性别、收缩压、舒张压与非血栓组对比,差异均无统计学意义(P>0.05)。血栓组左心房(LA)前后径、左右径均显著大于非血栓组(P<0.05),血栓组LAA血流最大排空速度、血流最大充盈速度均显著低于非血栓组(P<0.05)。血栓组LAA开口宽度指数(LAA-WI)、LAA开口面积指数(LAA-OI)、LAA开口长度指数(LAA-LI)均显著高于非血栓组(P<0.05)。Pearson分析显示,LA前后径、左右径、LAA-WI、LAA-OI、LAA-LI均与血栓形成呈正相关(P<0.05),LAA血流最大排空速度、LAA血流最大充盈速度均与血栓形成呈负相关(P<0.05)。结论:有血栓的房颤患者经食管实时三维超声心动图评价多伴有LA、LAA结构与功能异常,且LAA功能与血栓形成存在相关性。Objective:To explore and analyze the evaluation of left atrial appendage(LAA)function and its correlation with thrombosis in patients with atrial fibrillation by transesophageal real-time three-dimensional echocardiography.Method:A total of 60 patients with atrial fibrillation diagnosed and treated in the Second Affiliated Hospital of Baotou Medical College of Inner Mongolia University of Science and Technology from January 1st,2021 to August 1st,2022 were selected as the research subjects.All patients were given transesophageal real-time three-dimensional echocardiography to observe the LAA function,judge the thrombosis situation,and analyze the correlation between thrombosis and LAA function.Result:Among the 60 patients,10 cases developed thrombus,accounting for 16.67%.There were no significant differences in atrial fibrillation type,body mass index,age,course of disease,gender,systolic pressure and diastolic pressure between thrombus group and non-thrombus group(P>0.05).The anterior-posterior and left-right diameters of the left atrium(LA)in the thrombus group were significantly bigger than those in the non-thrombus group(P<0.05),and the maximum blood flow emptying velocity and the maximum blood flow filling velocity of the LAA in the thrombus group were significantly lower than those in the non-thrombus group(P<0.05).The LAA width index(LAA-WI),LAA open area index(LAA-OI)and LAA length index(LAA-LI)in the thrombus group were significantly higher than those in the non-thrombus group(P<0.05).Pearson analysis showed that the anterior-posterior and left-right diameters of the LAA,and LAA-WI,LAA-OI,LAA-LI were all positively correlated with thrombosis(P<0.05),while the maximum blood flow emptying velocity and the maximum blood flow filling velocity of the LAA were negatively correlated with thrombosis(P<0.05).Conclusion:Atrial fibrillation patients with thrombus are often accompanied by structural and functional abnormalities of LA and LAA evaluated by transesophageal real-time three-dimensional echocardiography,a

关 键 词：血栓形成 房颤 经食管实时三维超声心动图 左心房 左心耳 相关性 

分 类 号：R541.75[医药卫生—心血管疾病] R540.45[医药卫生—内科学]