酮咯酸氨丁三醇超前镇痛联合术后自控静脉镇痛对全髋关节置换术后患者的镇痛效果观察  

Observation on the analgesic effect of Ketorolac tromethamine preemptive analgesia combined with postoperative patientcontrolled intravenous analgesia on patients after total hip arthroplasty

作　　者：刘亚群 王艳 张庆璇 LIU Yaqun;WANG Yan;ZHANG Qingxuan(Department of Orthopaedics,Linyi Central Hospital,Linyi,Shandong 276400,China;Department of Cardiovascular Medicine,Linyi Central Hospital,Linyi,Shandong 276400,China;Department of Anesthesiology,Linyi Central Hospital,Linyi,Shandong 276400,China)

机构地区：[1]临沂市中心医院骨科,山东临沂276400 [2]临沂市中心医院心血管内科,山东临沂276400 [3]临沂市中心医院麻醉科,山东临沂276400

出　　处：《医药前沿》2023年第4期41-43,共3页Journal of Frontiers of Medicine

摘　　要：目的:观察酮咯酸氨丁三醇超前镇痛联合术后自控静脉镇痛对全髋关节置换术后患者的镇痛效果。方法:选取2021年1月—2022年10月临沂市中心医院收治的全髋关节置换术的患者70例,采用随机数字表法分为观察组和对照组各35例。对照组仅采用术后自控静脉镇痛,观察组则应用酮咯酸氨丁三醇超前镇痛联合术后自控静脉镇痛。比较两组术后12、24 h内镇痛泵按压次数、术后2、6、12、24 h各时间点视觉模拟评分(VAS)以及药物不良反应发生率。结果:观察组术后12、24 h内镇痛泵按压次数少于对照组,差异有统计学意义(P<0.01)。观察组术后2、6、12、24 h VAS评分低于对照组,差异有统计学意义(P<0.01)。观察组和对照组药物不良反应合计发生率分别为25.71%和20.00%,差异无统计学意义(P>0.05)。结论:酮咯酸氨丁三醇超前镇痛联合术后自控静脉镇痛用于全髋关节置换术,具有良好的术后镇痛效果,且能够减少术后镇痛药物的用量,安全性高,值得临床应用。Objective To observe the analgesic effect of Ketorolac tromethamine preemptive analgesia combined with postoperative patient-controlled intravenous analgesia on patients after total hip arthroplasty.Methods From January 2021 to October 2022,70 patients who underwent total hip arthroplasty in Linyi Central Hospital were selected and randomly divided into the observation group and the control group with 35 patients in each group.The control group used postoperative patient-controlled intravenous analgesia,and the observation group used Ketorolac tromethamine preemptive analgesia combined with postoperative patient-controlled intravenous analgesia.The times of pressing analgesia pump within 12 and 24 hours after operation,the scores of VAS at 2,6,12 and 24 hours after operation and the adverse drug reactions were compared between the two groups.Results The times of pressing analgesia pump in the observation group within 12 and 24 hours after operation were signifcantly less than those in the control group(P<0.01).The VAS score of the observation group was lower than that of the control group at 2,6,12 and 24 hours after operation(P<0.01).The incidence of adverse drug reactions in the observation group and the control group was 25.71%and 20.00%respectively,with no statistically signifcant difference(P>0.05).Conclusion Ketorolac tromethamine preemptive analgesia combined with postoperative patient-controlled intravenous analgesia for total hip replacement has a good postoperative analgesic effect,and can reduce the amount of postoperative analgesic drugs,with high safety,and is worthy of clinical application.

关 键 词：酮咯酸氨丁三醇 地佐辛 超前镇痛 全髋关节置换术 自控静脉镇痛 

分 类 号：R543.6[医药卫生—心血管疾病]