口服盐酸丙卡特罗联合吸入用布地奈德混悬液治疗喘息性支气管炎患儿的临床探讨  

Clinical Study of Oral Procaterol Hydrochloride Combined with Inhaled Budesonide Suspension in the Treatment of Asthmatic Bronchitis in Children

作　　者：张延辉 严琳 沈淑珍 ZHANG Yanhui;YAN Lin;SHEN Shuzhen(Zhangzhou Hospital Affiliated to Fujian Medical University,Zhangzhou 363000,China)

机构地区：[1]福建医科大学附属漳州市医院,福建漳州363000

出　　处：《中国医药指南》2023年第10期26-29,共4页Guide of China Medicine

摘　　要：目的对口服盐酸丙卡特罗联合吸入用布地奈德混悬液治疗喘息性支气管炎患儿的临床疗效加以探讨和分析。方法选取我院2022年1月至2022年12月接收的喘息性支气管炎患儿98例展开研究,按照随机数字表法原则分成对照组和观察组,每组49例,均进行常规对症治疗,对照组采取盐酸丙卡特罗口服治疗,观察组在对照组基础上联合吸入用布地奈德混悬液治疗。对比两组患儿的治疗效果。结果对照组患儿的治疗总有效率(81.63%)显著低于观察组(100.00%),数据差异具有统计学意义(P<0.05)。对照组患儿的各项临床症状消失时间均显著长于观察组(P<0.05)。治疗后,观察组患儿的PSQI各项评分均显著低于对照组(P<0.05)。治疗前,两组患儿的SaO_(2)及炎性因子水平差异无统计学意义(P>0.05);治疗后,观察组患儿的SaO_(2)水平高于对照组,炎性因子IL-6、IL-8水平低于对照组,组间对比差异显著(P<0.05)。治疗前,两组患儿SAS和SDS评分无明显差异(P>0.05);治疗后,观察组患儿SAS和SDS评分均显著低于对照组(P<0.05)。结论口服盐酸丙卡特罗联合吸入用布地奈德混悬液治疗喘息性支气管炎疗效显著。Objective To explore and analyze the clinical efficacy of oral procaterol hydrochloride combined with inhaled budesonide suspension in the treatment of asthmatic bronchitis in children.Methods Ninety-eight children with asthmatic bronchitis received in our hospital from January 2022 to December 2022 were selected for the study.They were divided into the control group and the observation group according to the principle of random number table.49 patients in each group were treated with routine symptomatic treatment.The control group was treated with oral procaterol hydrochloride.The observation group was treated with budesonide suspension inhalation on the basis of the control group.The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the control group(81.63%)was significantly lower than that in the observation group(100.00%),and the data difference was statistically significant(P<0.05).The clinical symptoms in the control group were significantly longer than those in the observation group(P<0.05).After treatment,the PSQI scores of children in the observation group were significantly lower than those in the control group(P<0.05).Before treatment,there was no significant difference in the levels of SaO_(2) and inflammatory factors between the two groups(P>0.05);after treatment,the level of SaO_(2) in the observation group was higher than that in the control group,and the levels of inflammatory factors IL-6 and IL-8 were lower than that in the control group,with significant differences between the groups(P<0.05).Before treatment,there was no significant difference in SAS and SDS scores between the two groups(P>0.05);after treatment,the SAS and SDS scores of children in the observation group were significantly lower than those in the control group(P<0.05).Conclusion Oral procaterol hydrochloride combined with inhaled budesonide suspension is effective in the treatment of asthmatic bronchitis.

关 键 词：喘息性支气管炎 盐酸丙卡特罗 布地奈德混悬液 临床疗效 

分 类 号：R562.21[医药卫生—呼吸系统]