m^(6)A-modified RNAs possess distinct poly(A)tails  

作　　者：Shuang Wu Yiwei Zhang Lan Yao Jiaqiang Wang Falong Lu Yusheng Liu 

机构地区：[1]College of Life Science,Northeast Agricultural University,Harbin,Hei Longjiang 150030,China [2]State Key Laboratory of Molecular Developmental Biology,Institute of Genetics and Developmental Biology,Innovative Academy of Seed Design,Chinese Academy of Sciences,Beijing 100101,China [3]University of Chinese Academy of Sciences,Beijing 100049,China [4]College of Life Science,Northeast Forestry University,Harbin,Hei Longjiang 150040,China

出　　处：《Journal of Genetics and Genomics》2023年第3期208-211,共4页遗传学报（英文版）

基　　金：supported by the National Key Research and Development Program of China(2020YFA0804000);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA24020203);the CAS Project for Young Scientists in Basic Research(YSBR-012);the National Natural Science Foundation of China(31970588,32170606,32201060);the Natural Science Foundation of Heilongjiang province(YQ2020C003);the China Postdoctoral Science Foundation(2020M670516,2020T130687);the State Key Laboratory of Molecular Developmental Biology。

摘　　要：N^(6)-methyladenosine(m^(6)A)has been found to be the most common type of post-transcriptional chemical modification in mammalian mRNAs and long non-coding RNAs(lncRNAs)(Dominissini et al.,2012;Meyer et al.,2012).In both mammals and yeast,RNA m^(6)A preferentially occurs in both gene coding regions and 3’untranslated regions(3’-UTRs),implicating its fundamental roles in every aspect of post-transcriptional regulation,including splicing,stability,and translation(Wang et al.,2014,2015;Zhao et al.,2014;Yang et al.,2018b).

关 键 词：N^(6)-methyladenosine(m^(6)A) preferentially 

分 类 号：Q75[生物学—分子生物学]