伤科止痛膏肌内效贴治疗踝关节扭伤疗效观察  

Effect of Shangke Zhitong Ointment Kinesio Tape on Ankle Sprain

作　　者：王强[1] 刘志杨 巨少华[1] 黎小东 黄继超 向宁 WANG Qiang;LIU Zhiyang;JU Shaohua;LI Xiaodong;HUANG Jichao;XIANG Ning(Hospital of Physical Education Affiliated to Chengdu Institute of Physical Education,Chengdu,Sichuan 610041,China;Hunan Provincial Sports Medical Specialized Hospital,Changsha,Hunan 410008,China)

机构地区：[1]成都体育学院附属体育医院,四川成都610041 [2]湖南省体育运动医疗专科医院,湖南长沙410008

出　　处：《康复学报》2023年第2期160-166,共7页Rehabilitation Medicine

基　　金：四川省科技计划项目(2018JY0264);四川省中医药管理局项目(2021ms503);成都体育学院郑怀贤骨伤研究所2021创新课题(GS21ZX03)。

摘　　要：目的:观察伤科止痛膏肌内效贴治疗踝关节扭伤患者的临床疗效。方法:选取2021年1—10月在成都体育学院附属体育医院治疗的踝关节扭伤患者123例,采用随机数字表法分为对照组、联用组和伤科肌贴组,每组41例。3组均遵循急性损伤PRICE基本原则进行基础治疗。此外,对照组接受单纯肌内效贴治疗;联用组接受肌内效贴联合伤科止痛膏治疗;伤科肌贴组接受伤科止痛膏肌内效贴治疗。3组每日更换1次敷贴,5次/周,持续治疗2周。3组分别于治疗前、治疗2周后进行疼痛视觉模拟评分(VAS)、肿胀程度测量、美国足踝骨科协会踝-后足评分(AOFAS-AHS)、中医证候积分(局部压痛、局部肿胀、局部瘀血、活动受限)评价、实验室指标检测[白细胞介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)、超氧化物歧化酶(SOD)、丙二醛(MDA)、成纤维细胞生长因子-2(FGF-2)、转化生长因子-β1(TGF-β1)、基质金属蛋白酶-9(MMP-9)]及皮肤不良反应观察。结果:①VAS评分、踝关节肿胀程度和AOFAS-AHS评分:与治疗前比较,3组治疗后VAS评分、肿胀程度明显降低,AOFAS-AHS评分明显升高(P<0.05)。与对照组比较,联用组和伤科肌贴组治疗后VAS评分、肿胀程度明显更低,AOFAS-AHS评分明显更高(P<0.05)。与联用组比较,伤科肌贴组治疗后肿胀程度明显更低,AOFAS-AHS评分明显更高(P<0.05)。②中医证候积分:与治疗前比较,3组治疗后局部压痛、局部肿胀、局部瘀血、活动受限积分明显降低(P<0.05)。与对照组比较,联用组和伤科肌贴组治疗后局部压痛、局部肿胀、局部瘀血、活动受限积分明显更低(P<0.05)。与联用组比较,伤科肌贴组治疗后局部肿胀、活动受限积分明显更低(P<0.05)。③实验室检查:与治疗前比较,3组治疗后血清IL-1β、TNF-α、MDA、FGF-2、TGF-β1、MMP-9水平明显降低,SOD水平明显升高(P<0.05)。与对照组比较,联用组治疗后血清IL-1β、TNF-Objective:To observe the effect of Shangke Zhitong ointment kinesio tape on ankle sprain.Methods:A total of 123 patients with ankle sprain in the Hospital of Physical Education Affiliated to Chengdu Institute of Physical Education from January to October 2021 were randomly divided into control group,combined group and Shangke kinesio tape group,with 41 cases in each group.All groups were treated following the basic principles of PRICE for acute injury.In addition,the control group received kinesio tape therapy;the combined group received kinesio tape and Shangke Zhitong ointment;the Shangke kinesio tape group received Shangke Zhitong ointment kinesio tape.The three groups changed the application once a day,five times a week,lasting for two weeks.Before treatment and after two weeks of treatment,visual analogue score(VAS),swelling degree measurement,American orthopedic foot and ankle society-ankle hindfood scale(AOFAS-AHS),traditional Chinese medicine(TCM)syndrome score(local tenderness,local swelling,local blood stasis,limited activity)were evaluated,and laboratory index test[interleukin-1β(IL-1β),tumor necrosis factor-α(TNF-α),superoxide dismutase(SOD),malondialdehyde(MDA),fibroblast growth factor-2(FGF-2),transforming growth factor-β1(TGF-β1),matrix metalloproteinase(MMP-9)]were performed and skin adverse reactions were observed.Results:(1)VAS score,swelling degree of ankle joint and AOFAS-AHS score:compared with before treatment,VAS score and swelling degree in the three groups decreased significantly after treatment,while AOFAS-AHS score increased significantly after treatment(P<0.05).Compared with the control group,the VAS score and swelling degree were significantly lower in the combined treatment group and the Shangke kinesio tape group after treatment,and the AOFAS-AHS score was significantly higher(P<0.05).Compared with the combined group,the degree of swelling in the Shangke kinesio tape group after treatment was significantly lower,and the AOFAS-AHS score was significantly higher(P<0.05).(2)TCM s

关 键 词：踝关节扭伤 伤科止痛膏 中药伤科 肌内效贴 足踝功能 

分 类 号：R274.9[医药卫生—中西医结合]