复方芩兰口服液抗病毒物质基础及作用机制研究进展  

Research progress of antiviral material basis and mechanism of Compound Qinlan Oral Liquid

作　　者：闫久江 孟杰 刘树民[2] 索迪 颜正华[3] YAN Jiu-jiang;MENG Jie;Liu Shu-min;SUO Di;YAN Zheng-hua(Pharmaceutical Research Institute,Zhenbaodao Pharmaceutical Co.,Ltd.,Harbin 150060,China;Institute of Traditional Chinese Medicine,Heilongjiang University of Chinese Medicine,Harbin 150040,China;Guoyitang Traditional Chinese Medicine Hall,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]珍宝岛药业股份有限公司药物研究院,黑龙江哈尔滨150060 [2]黑龙江中医药大学中医药研究院,黑龙江哈尔滨150040 [3]北京中医药大学国医堂中医馆,北京100029

出　　处：《中草药》2023年第6期2005-2011,共7页Chinese Traditional and Herbal Drugs

摘　　要：复方芩兰口服液(Compound Qinlan Oral Liquid,CQOL)由银翘散化裁而来,由金银花Lonicerae Japonicae Flos、黄芩Scutellariae Radix、连翘Forsythiae Fructus、板蓝根Isatidis Radix组成,是临床上常用的清热解毒类中药,具有抗病毒作用。通过对CQOL的有效成分、抗流感病毒和新型冠状病毒(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)药效研究进展等进行综述,为CQOL临床用于治疗SARS-CoV-2引起的呼吸道疾病提供依据。Compound Qinlan Oral Liquid(复方芩兰口服液,CQOL)is derived from Yinqiao San(银翘散),which is composed of Jinyinhua(Lonicerae Japonicae Flos),Huangqin(Scutellariae Radix),Lianqiao(Forsythiae Fructus)and Banlangen(Isatidis Radix).It is a common clinical herbal medicine for clearing heat and detoxification,and has antiviral effects.By reviewing the active ingredients of CQOL and the research progress on its anti-influenza virus and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)efficacy,with view to providing a basis for the clinical use of CQOL in treatment of respiratory diseases caused by SARS-CoV-2.

关 键 词：复方芩兰口服液 抗病毒 中医理论 物质基础 药效学研究 绿原酸 黄芩苷 木脂素 生物碱 

分 类 号：R285[医药卫生—中药学]