多模式量化康复运动在强直性脊柱炎患者中的应用效果  

Application effect of multimodal quantitative rehabilitation exercise in patients with ankylosing spondylitis

作　　者：高翠荣[1] 李晖[2] 李芳昱 邵玉敏 Gao Cuirong;Li Hui;Li Fangyu;Shao Yumin(Department of Rheumatology and Immunology,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China;Department of Medical VIP Ward I,First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院风湿免疫科,乌鲁木齐830054 [2]新疆医科大学第一附属医院内科VIP一病区,乌鲁木齐830054

出　　处：《中国实用护理杂志》2023年第8期593-598,共6页Chinese Journal of Practical Nursing

基　　金：新疆维吾尔自治区自然科学基金资助项目(2021D01C303)。

摘　　要：目的探讨多模式量化康复运动在强直性脊柱炎患者中的应用效果,为患者康复锻炼提供参考。方法本研究为类实验研究。便利抽取新疆医科大学第一附属医院风湿免疫科2021年2月至2022年2月住院的强直性脊柱炎患者78例作为研究对象。将2021年2—8月入院的39例患者作为对照组,采用常规康复运动方案;2021年9月至2022年2月入院的39例患者作为试验组,采用多模式量化康复运动方案。比较干预6个月后2组Bath强直性脊柱炎疾病活动指数、功能指数及炎症因子含量。结果干预6个月试验组患者的Bath强直性脊柱炎疾病活动指数得分为(2.35±0.81)分,对照组为(3.47±1.04)分,差异有统计学意义(t=4.02,P<0.05);2组患者的Bath强直性脊柱炎疾病活动指数得分采用重复测量方差分析,时间效应、组间效应和交互效应的差异均有统计学意义(F组间=11.27、F时间=62.05、F交互=5.47,均P<0.05)。干预6个月试验组患者的Bath强直性脊柱炎功能指数为(2.11±0.32)分,对照组为(3.07±0.58)分,差异有统计学意义(t=4.03,P<0.05);2组患者的Bath强直性脊柱炎功能指数得分采用重复测量方差分析,时间效应、组间效应和交互效应的差异均有统计学意义(F组间=21.44、F时间=42.25、F交互=16.67,均P<0.05)。干预6个月试验组患者的C反应蛋白、白细胞介素-6、转化生长因子β、肿瘤坏死因子-α分别为(43.15±2.21)mg/L、(3.28±0.85)mg/L、(41.67±9.04)ng/L、(176.63±20.15)ng/L,对照组分别为(50.12±1.67)mg/L、(5.27±0.68)mg/L、(48.65±8.96)ng/L、(194.56±19.45)ng/L,2组患者炎症因子含量比较差异均有统计学意义(t值为2.05~4.45,均P<0.05)。结论多模式量化康复运动能改善强直性脊柱炎患者脊柱生理功能,减轻患者的疾病活动度,从而促进患者康复。Objective To explore the application effect of multimodal quantitative rehabilitation exercise in patients with ankylosing spondylitis and to provide reference for patients′rehabilitation exercise.Methods The quasi-experimental study method was used to select 78 patients with ankylosing spondylitis admitted to Rheumatology and Immunology Department of First Affiliated Hospital of Xinjiang Medical University from February 2021 to February 2022 as the research objects.The 39 patients admitted from February 2021 to August 2021 as the control group,and 39 patients admitted from September 2021 to February 2022 as the experimental group.The control group adopted conventional rehabilitation exercise program,and the experimental group adopted multimodal quantitative rehabilitation exercise program.The Bath ankylosing spondylitis disease activity index,Bath ankylosing spondylitis function index,inflammatory factors after 6 months of intervention were compared between the two groups.Results The Bath ankylosing spondylitis disease activity index in the experimental group after 6 months of intervention was(2.35±0.81)points,and that in the control group was(3.47±1.04)points,with a statistically significant difference(t=4.02,P<0.05).The Bath ankylosing spondylitis disease activity index in the two groups were analyzed by repeated measurement variance.The differences of time effect,inter group effect and interaction effect were statistically significant(Fgroup=11.27,Ftime=62.05,Finteraction=5.47,all P<0.05).The Bath ankylosing spondylitis function index in the experimental group after 6 months of intervention was(2.11±0.32)points,and that in the control group was(3.07±0.58)points,with a statistically significant difference(t=4.03,P<0.05).The Bath ankylosing spondylitis function index in the two groups were analyzed by repeated measurement variance.The differences in time effect,inter group effect and interaction effect were statistically significant(Fgroup=21.44,Ftime=42.25,Finteraction=16.67,all P<0.05).After 6 months of

关 键 词：强直性脊柱炎 多模式量化康复运动 应用效果 

分 类 号：R593.23[医药卫生—内科学] R493[医药卫生—临床医学]