脱细胞真皮基质对烧伤损伤修复的研究进展  

Research progress of acellular dermal matrix in the repair of burn injury

作　　者：刘顺财 肖玲 陈玲 王志锋 陆巍[1] 蒋晓臣 薛永平 LIU Shun-cai;XIAO Ling;CHEN Ling;WANG Zhi-feng;LU Wei;JIANG Xiao-chen;XUE Yong-ping(Affiliated Hospital of Guilin Medical College,the Guangxi Zhuang Autonomous Region,541000,China;Southwest Hospital of the Army Military Medical University,Chongqing City,400000,China)

机构地区：[1]桂林医学院附属医院,广西桂林541000 [2]陆军军医大学西南医院,重庆400000

出　　处：《中国医疗美容》2023年第2期54-57,共4页China Medical Cosmetology

基　　金：GM-CSF促进放射性溃疡创面修复的基础及临床研究(课题编号:Z20211123)。

摘　　要：严重烧伤是一种极具创伤性、致死率高的疾病,其治疗一直是烧伤整形外科中的难点,而脱细胞真皮基质(Acellular dermal matrix,ADM)因为具有基底膜较完整、生物相容性良好和可“永久性”存在等优点,推动了烧伤整形修复的发展。脱细胞异体真皮已成为目前国内外业内认可的“永久性”真皮的替代原料。迄今为止,已有数万名患者从中受益并重拾健康。本文就近年来ADM的理化性能、临床应用及作用机制等方面做了阐述,希望给严重烧伤治疗提供指导。Severe burn is a highly traumatic and fatal disease,and its treatment has always been a difficult point in burn plastic surgery.Acellular dermal matrix(Acellular dermal matrix,ADM)has the advantages of complete basement membrane,good biocompatibility and"permanent"existence,which promotes the development of burn plastic repair.Acellular allogenic dermis has become a substitute for"permanent"dermis recognized by the industry at home and abroad.So far,tens of thousands of patients have benefited and regained their health.This article describes the physical and chemical properties,clinical application and mechanism of ADM in recent years,hoping to provide guidance for the treatment of severe burns.

关 键 词：脱细胞真皮基质 烧伤 修复 

分 类 号：R644[医药卫生—外科学]