同侧多发性亚厘米肺结节影像学特征同临床病理相关研究  

The Relationship between Imaging and Clinical Pathology of Ipsilateral Multiple Sub Centimeter Pulmonary Nodules

作　　者：冷雪春 尤振兵[1] 徐克平[1] 韩东 张瑞瑞 胡忠吾[1] 李朋玲[4] LENG Xue-chun;YOU Zhen-bing;XU Ke-ping;HAN Dong;ZHANG Rui-rui;HU Zhong-wu;LI Peng-ling(Thoracic Surgery Department,Huai'an First Hospital Affiliated to Nanjing Medical University,Nanjing 223300,Jiangsu Province,China;Imaging Department of Huai'an First Hospital Affiliated to Nanjing Medical University,Nanjing 223300,Jiangsu Province,China;Department of Pathology,Huai'an First Hospital Affiliated to Nanjing Medical University,Nanjing 223300,Jiangsu Province,China;Respiratory Department of Huai'an First Hospital Affiliated to Nanjing Medical University,Nanjing 223300,Jiangsu Province,China)

机构地区：[1]南京医科大学附属淮安一院胸外科,江苏南京223300 [2]南京医科大学附属淮安一院影像科,江苏南京223300 [3]南京医科大学附属淮安一院病理科,江苏南京223300 [4]南京医科大学附属淮安一院呼吸科,江苏南京223300

出　　处：《中国CT和MRI杂志》2023年第4期41-43,共3页Chinese Journal of CT and MRI

基　　金：淮安市卫生健康科研项目(HAWJ201909)。

摘　　要：目的 分析同侧亚厘米多发性肺小结节,影像学特点和临床病理关系。方法 收集2016年1月到2022年8月在南京医科大学附属淮安一院行手术切除的40例亚厘米同侧多发肺结节患者的临床资料,分成良性组、腺瘤样增生组、肺癌组,分析影像学特点和临床病理关系。结果 40例患者共切除结节100枚,良性结节12枚(12%),腺瘤样增生(AAH)15枚(15%),原位癌(AIS)21枚(21%),微浸润腺癌(MIA)28枚(28%),浸润性腺癌(IA)24枚(24%);纯磨玻璃71例(71%)亚实性磨玻璃结节10枚(10%),实性19枚(19%);直径大于6mm、和肺组织边界清晰、磨玻璃形态、空泡征、毛刺征在肺癌比例较高(P<0.05),实性结节良性可能高。结论 亚厘米多发肺小结节高危病变的影像学特征和临床病理存在相关性。Objective To analyze the imaging characteristics and clinicopathological relationship of ipsilateral subcellular multiple pulmonary nodules.Method From January 2016 to August 2022,the clinical data of 40 patients with subccm ipsilateral multiple pulmonary nodules who were surgically resected in Huai'an First Hospital affiliated to Nanjing Medical University were collected and divided into benign group,adenomatous hyperplasia group and lung cancer group.The imaging characteristics and clinicopathological relationship were analyzed.Results A total of 100 nodules,12 benign nodules(12%),15 adenomatous hyperplasia(15%),21 carcinoma in situ(AIS),28 minimally invasive adenocarcinoma(MIA),and 24 invasive adenocarcinoma(IA)were removed in 40 patients;In 71 cases(71%)of pure ground glass,10(10%)were sub solid ground glass nodules,and 19(19%)were solid ground glass nodules;The proportion of lung cancer with diameter greater than 6 mm,clear border with lung tissue,ground glass morphology,vacuole sign and hairpin sign is higher(P<0.05),and solid nodules may be more benign.Conclusion The imaging characteristics of the high risk pulmonary nodules with the sub centimeter multiple lesions are correlated with the clinical pathology.

关 键 词：多发性肺结节 亚厘米 CT 诊断 病理 

分 类 号：R445.3[医药卫生—影像医学与核医学]