香附炮制的历史沿革及研究现状  

Historical evolution and research status of processing of Cyperi Rhizoma

作　　者：陈一龙[1] 励娜[1] 储瑞 李胜容[1] CHEN Yi-long;LI Na;CHU Rui;LI Sheng-rong(Chongqing Engineering Research Center of Pharmaceutical Evaluation of Chinese Medicine,Chongqing Academy of Chinese Materia Medica,Chongqing 400065,China)

机构地区：[1]重庆市中药研究院、重庆市中药药学评价工程技术研究中心,重庆400065

出　　处：《天然产物研究与开发》2023年第4期722-731,共10页Natural Product Research and Development

基　　金：重庆市卫生计生委中医药科技项目(ZY201802297);重庆市自然科学基金面上项目(cstc2019jcyj-msxmX0658);重庆市卫生健康委员会中药炮制学重点学科建设项目(渝中医[2022]7号);重庆市现代山地特色高效农业中药材产业技术体系(2022【10】号)。

摘　　要：香附为妇科常用药,被认为是调经止痛之要药,临床上一般炮制后使用。本文梳理《中国药典》与各省市炮制规范中关于香附的炮制情况,以及不同炮制品中医理论的功效和现代药理作用,并整理归纳了炮制后的药效物质基础和作用机理。对香附炮制规范的完善和提高、炮制后活性成分及作用机理的发现与探索进行展望,为香附炮制的深入研究提供参考。Cyperi Rhizoma,the rhizome of Cyperus rotundus L.,is commonly used in gynecology,which is considered to be the most important drug for regulating of painful menstruation.It is generally used after processing in clinic.In this paper,the processing methods of Cyperi Rhizoma in the Chinese Pharmacopoeia and the processing specifications of various provinces were summarized.As well as the efficacy of TCM theories and pharmacological effects of different processed products,and the basis of medicinal substances and mechanism of action after processing were summarized.The perfection and improvement of processing specifications of Cyperi Rhizoma,the discovery of other effective components and the exploration of action mechanism were prospected.It can provide reference for the in-depth study of the processing of Cyperi Rhizoma.

关 键 词：香附 炮制 历史沿革 药效物质基础 作用机理 

分 类 号：R284[医药卫生—中药学]