超脉冲二氧化碳点阵激光联合强脉冲光治疗面部痤疮凹陷性瘢痕的疗效分析  

Curative effect analysis of ultrapulse carbon dioxide fractional laser combined with intense pulsed light in treating depressed scars after acne

作　　者：闫美荣 李忠贤 朱世花 周生虎[1] 王艳荣[1] 梁仁章 YAN Mei-rong;LI Zhong-xian;ZHU Shi-hua;ZHOU Sheng-hu;WANG Yan-rong;LIANG Ren-zhang(Department of burn and plastic surgery,General Hospital of Ningxia Medical University,Ningxia Hui Autonomous Region,750004,China;Department of Pediatric Surgery,PKUFH-NINGXIA WOMEN CHILDRE’S HOSPTAL,Ningxia Hui Autonomous Region,750000,China)

机构地区：[1]宁夏医科大学总医院烧伤整形美容科,宁夏银川750004 [2]北京大学第一医院宁夏妇女儿童医院小儿外科,宁夏银川750000

出　　处：《中国医疗美容》2023年第4期17-21,共5页China Medical Cosmetology

基　　金：宁夏医科大学2022年校级课题重点项目(编号:XZ2022024)。

摘　　要：目的 探讨超脉冲二氧化碳点阵激光联合强脉冲光治疗面部痤疮凹陷性瘢痕的疗效分析。方法 选取笔者医院2020年1月-2022年12月面部痤疮凹陷性瘢痕患者92例,依据随机数字表法将患者分为2组,研究组和对照组分别为46例。研究组给予超脉冲二氧化碳点阵激光联合强脉冲光治疗,对照组单纯给予超脉冲二氧化碳点阵激光治疗,比较两组临床治疗有效率、痤疮瘢痕临床评分量表(ECCA)权重评分、皮肤屏障功能指标及不良反应发生情况。结果 研究组临床治疗总有效率(95.65%)高于对照组(78.26%),差异有统计学意义(P <0.05)。研究组治疗后ECCA权重评分低于对照组,且两组组内治疗前后ECCA权重评分对比,差异有统计学意义(P <0.05)。研究组治疗后皮肤屏障功能指标明显优于对照组,差异有统计学意义(P <0.05)。结论 超脉冲二氧化碳点阵激光联合强脉冲光治疗面部痤疮凹陷性瘢痕临床疗效显著,明显提高皮肤屏障功能,改善痤疮凹陷性瘢痕患者的ECCA权重评分,安全性高,适宜临床推广应用。Objective To investigate the curative effect analysis ultrapulse carbon dioxide fractional laser(UCFL)combined with intense pulsed light in treating depressed scars after acne.Methods 92 patients with acne scar admitted in our hospital from January 2020 to December 2022 were divided into study group(n=46)and control group(n=46)on the basis of random number table.The study group was administrated with UCFL and Intense Pulsed Light,while the control group was administrated with UCFL only.The clinical efficacy,clinical acne scar assessment scale(ECCA)weight scores,skin barrier function index as well as occurrence of side effect were compared between the two groups.Results The total effective rate of the study group(95.65%)was higher than that of the control group(78.26%),the difference was statistically significant(P<0.05).The ECCA weight score of the study group after treatment was lower than that of the control group,and the ECCA weight score before and after treatment in the two groups was compared,the difference was statistically significant(P<0.05).After treatment,the skin barrier function index of the study group was significantly better than that of the control group,and the difference was statistically significant(P<0.05).Conclusion UCFL combined with intense pulsed light has significant clinical effect in the treatment of depressed acne scars on face,which is helpful to improve skin barrier function and ECCA weight score of patients with depressed acne scars.This combined therapy is safe and suitable for clinical application.

关 键 词：痤疮凹陷性瘢痕 超脉冲二氧化碳点阵激光 强脉冲光 临床疗效 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]