不同耐力素质军人进驻高原前后生化指标的变化  

Alterations of biochemical indicators in military personnel with different endurance qualities before and after high altitude exposure

作　　者：李松 杨丽君 倪振洪 旷梁 杨京 张统一 伍锦辉 黄博 邬晓薇[4] 杜江[5] 李晓波[5] 吕雪 罗灵 孟涛[5] 陈增辉[5] 胡绪[5] 李海明[5] 田中原 李晓琦 胡彦[5] 陈林 LI Song;YANG Lijun;NI Zhenhong;KUANG Liang;YANG Jing;ZHANG Tongyi;WU Jinhui;HUANG Bo;WU Xiaowei;DU Jiang;LI Xiaobo;LYU Xue;LUO Ling;MENG Tao;CHEN Zenghui;HU Xu;LI Haiming;TIAN Zhongyuan;LI Xiaoqi;HU Yan;CHEN Lin(State Key Laboratory of Trauma,Burns and Combined Injury,Laboratory of Battle Injury Repair and Rehabilitation Medicinet,Army Medical Center of PLA,Chongqing,400042;College of Basic Medical Sciences,Army Medical University(Third Military Medical University),Chongqing,400038;Department of Rehabilitation Medicinet,Army Medical Center of PLA,Chongqing,400042;Department of Teaching Management,Army Medical University(Third Military Medical University),Chongqing,400038;Department of Military Basic Training and Army Management,Army Medical University(Third Military Medical University),Chongqing,400038;Department of Teaching Managementt,Army Medical Center of PLA,Chongqing,400042;Department of Obstetrics and Gynaecologyt,Army Medical Center of PLA,Chongqing,400042;Political Department,Army Medical Center of PLA,Chongqing,400042;Department of Economics and Medical Insurance Management,No.958 Hospital of Army,Chongqing,400020,China)

机构地区：[1]陆军特色医学中心战伤组织修复与康复医学研究室,重庆400042 [2]陆军军医大学(第三军医大学)基础医学院,重庆400038 [3]陆军特色医学中心康复医学科,重庆400042 [4]陆军军医大学(第三军医大学)教务处,重庆400038 [5]陆军军医大学(第三军医大学)军事共同与部队管理教研室,重庆400038 [6]陆军特色医学中心教务科,重庆400042 [7]陆军特色医学中心妇产科,重庆400042 [8]陆军特色医学中心政治部,重庆400042 [9]陆军第958医院经济与医保管理科,重庆400020

出　　处：《陆军军医大学学报》2023年第7期715-719,共5页Journal of Army Medical University

基　　金：中国人民解放军科研项目(2019ZLX001,2020XYY11,2021XQN22,21WQ0022)。

摘　　要：目的分析军人耐力素质及生化指标的变化,掌握不同耐力素质军人对高原环境适应情况。方法采取整群抽样法,纳入2018年7-8月前往云南马龙(海拔2100 m)驻训4周的男性青年军人253名,进行耐力素质、生化指标两个方面的调查。耐力素质指标为三公里武装越野成绩;生化指标为肌酸激酶、红细胞数目、血红蛋白浓度、平均血红蛋白浓度、心肌肌钙蛋白、淋巴细胞数目、嗜碱性细胞数目等7个项目。结果三公里武装越野成绩分布为4组,其中优秀占比12%、良好占比21%、及格占比40%,不及格占比27%。生化指标除嗜碱性粒细胞在4组中没有显著变化外,肌酸激酶、血红蛋白、平均血红蛋白浓度、红细胞数目、心肌肌钙蛋白、淋巴细胞数目等指标在4个组组内进驻高原前后均发生了显著性变化(P<0.01)。其中,心肌肌钙蛋白、淋巴细胞数目仅在进驻高原后发生了4组组间的差异性变化(P<0.01),且与耐力素质高低存在关联性,具有统计学差异(心肌肌钙蛋白rs=-0.409,P<0.01;淋巴细胞数目rs=0.205,P<0.01)。结论不同耐力素质军人在高原环境下的血液生化指标确实存在一定程度差异,提示耐力素质越高的军人进驻高原后发生心肌损伤的风险相对较低,且其免疫能力较强。ObjectiveTo explore the changes in biochemical indicators among soldiers with different endurance qualities after high altitude exposure and their adaptation to plateau environment.MethodsA status survey was carried out on 253 young male soldiers who were planned to station in Malone,Yunnan Province(2100 m)for 4 weeks from July to August,2018.The sampling method is cluster sampling.The endurance quality and biochemical indicators were assessed and measured before exposure and after 4 weeks’training.Their endurance quality was evaluated with grading 3-km armed cross-country.The included biochemical indicators were levels of creatine kinase,hemoglobin,average hemoglobin and cardiac troponin,and counts of blood red cells,lymphocytes and basophils.ResultsBased on the results of the 3-km armed cross-country,the participants were divided into excellent(12%),good(21%),passing(40%)and failing(27%)groups.Except for basophil counts,levels of creatine kinase,cardiac troponin,hemoglobin and average hemoglobin,and counts of red blood cells and lymphocyte changed significantly in all the 4 groups before and after high altitude exposure(P<0.01).While,obvious changes were observed in cardiac troponin level and lymphocyte count among the 4 groups after they were stationed at high altitude(P<0.01),and these changes were correlated with endurance quality(cardiac troponin:rs=-0.409,P<0.01;lymphocytes:rs=0.205,P<0.01).ConclusionThere are some differences in blood biochemical indicators in soldiers with different endurance qualities at high altitude.Our results suggest that soldiers with higher endurance quality have a relatively lower risk of myocardial injury and stronger immune function after entering high altitude.

关 键 词：高原 耐力素质 免疫功能 心肌损伤 

分 类 号：R339.54[医药卫生—人体生理学] R446.112[医药卫生—基础医学] R821.21