二甲硅油不同给药途径在儿童全身麻醉上消化道内镜检查中的研究  

Study on different routes of dimethylsilicone oil administration in upper gastrointestinal endoscopy under general anesthesia in children

作　　者：张杨 谢美燕 刘敏燕 钟晓燕 彭小燕 ZHANG Yang;XIE Meiyan;LIU Minyan;ZHONG Xiaoyan;PENG Xiaoyan(Department of Gastroenterology,Ganzhou Maternal and Child Health Hospital,Ganzhou,Jiangxi 341000,China)

机构地区：[1]江西省赣州市妇幼保健院儿童消化内科,江西赣州341000

出　　处：《检验医学与临床》2023年第8期1053-1056,共4页Laboratory Medicine and Clinic

基　　金：江西省卫生健康委科技计划项目(202212356)。

摘　　要：目的探讨儿童全身麻醉上消化道内镜检查期间二甲硅油不同给药途径的应用效果。方法选取2021年1月至2022年6月该院收治的60例全身麻醉上消化道内镜检查患儿作为研究对象,采用随机数字表法分为对照组和观察组,每组各30例。对照组患儿检查前给予二甲硅油治疗,观察组患儿检查中给予二甲硅油治疗,比较两组患儿依从性、全身麻醉上消化道内镜检查时间、病变检出率、黏膜视野清晰度、不良反应发生率。结果两组患儿治疗前血压、心率比较,差异均无统计学意义(P>0.05);观察组患儿治疗后血压、心率均低于对照组,差异均有统计学意义(P<0.05)。两组患儿不同部位病变检出率比较,差异均无统计学意义(P>0.05)。观察组患儿治疗后不良反应发生率与对照组比较,差异无统计学意义(P>0.05)。观察组患儿治疗后食管、胃底、胃体、胃角、十二指肠黏膜视野清晰度评分均低于对照组,差异均有统计学意义(P<0.05)。观察组患儿治疗后依从率高于对照组,差异有统计学意义(P<0.05)。观察组患儿治疗后需要冲洗的例数、冲洗时间及内镜检查时间均低于对照组,差异均有统计学意义(P<0.05)。结论对全身麻醉上消化道内镜检查患儿使用二甲硅油药物时,不同给药途径产生的疗效有较大差异,选择检查中给药可明显提高患儿的依从性,改善其黏膜视野清晰度,病变检出率更高,临床应用效果更明显。Objective To explore the effect of different administration routes of simethicone during upper gastrointestinal endoscopy in children under general anesthesia.Methods According to the random number table method,60 children with upper gastrointestinal endoscopy under general anesthesia who were treated from January 2021 to June 2022 were divided into groups(30 cases in each group).The patients in the control group were treated with dimethicone oil before test,while the patients in the observation group were treated with dimethicone oil during test.The compliance,upper gastrointestinal endoscopic examination time under general anesthesia,lesion detection rate,clear visual field of gastric mucosa,and incidence of adverse reactions were compared between the two groups.Results Before treatment,there was no difference in blood pressure and heart rate between the two groups(P>0.05).After treatment,the blood pressure and heart rate of patients in the observation group were lower than those in the control group,with significant differences(P<0.05).There was no significant difference in the detection rate of lesions at different sites between the two groups(P>0.05).There was no significant difference in the incidence of adverse reactions between the observation group and the control group after treatment(P>0.05).After treatment,the scores of gastroscopic mucosal visual field clarity in the esophagus,gastric fundus,gastric body,gastric horn,and duodenum in the observation group were significantly lower than those in the control group(P<0.05).The compliance rate of patients in the observation group after treatment was higher than that in the control group,with a statistically significant difference(P<0.05).The number of cases requiring irrigation,irrigation time,and endoscopic examination time in the observation group were significantly lower than those in the control group after treatment(P<0.05).Conclusion When using simethicone in children undergoing general anesthesia and upper gastrointestinal endoscopy,there are great

关 键 词：二甲硅油 给药途径 儿童 全身麻醉 上消化道内镜 依从性 

分 类 号：R445.9[医药卫生—影像医学与核医学]