吸气峰流速对吸入装置个体化选择的影响  

The Influence of the Peak Inspiratory Flow Rate for Individual Selection on

作　　者：冯婕 FENG Jie(Liuzhou Traditional Chinese Medical Hospital/Liuzhou Zhuang Medical Hospital,Liuzhou,Guangxi 545000,China)

机构地区：[1]柳州市中医医院/柳州市壮医医院,广西柳州545000

出　　处：《今日药学》2023年第2期128-131,共4页Pharmacy Today

摘　　要：吸入治疗在慢性呼吸道疾病如哮喘、慢性阻塞性肺病的治疗及管理中伴有重要角色[1-5]。吸入装置作为吸入药物递送的重要部件,直接影响吸入治疗的效果。吸气峰流速(peak inspiratory flow rate,PIFR)是指患者在使用不同吸入装置时,抵抗装置内部阻力所能产生的最大吸气流速,目前PIFR已被作为吸入装置个体化选择的主要考量指标[5-6]。本文将从常见的吸入装置分类和特点、PIFR与装置内部阻力的关系以及PIFR在吸入装置个体化选择中的应用3个方面进行综述,以为患者个体化选择适宜的装置。Inhalation therapies play an important role for the treatment and management of chronic respiratory diseses,especially chronic obstruction pulmonary disease and asthma.As an important drug delivery system,inhalers affect the therapeutic effect directly.Peak inspiratory flow rate(PIFR)refers to the maximum inspiratory flow rate that can be generated by resisting the internal resistance of the device for different inhalers which are the important aspect for individual selection on inhalers.In this article,the common classification,the characteristic and the relation of the PIFR between the internal resistance of the inhalers are reviewed,aiming to select an appropriate inhation device for individual patients.

关 键 词：吸气峰流速 吸入装置 慢性呼吸系统疾病 

分 类 号：R563.1[医药卫生—呼吸系统]