藏药复方白脉软膏配伍特点及其治疗白脉病的核心药物探析  

Compatibility Characteristics of Tibetan Medicine Compound Baimai Ointment and Analysis of Core Drugs in Treatment of Baimai Disease

作　　者：格知加 周杨措 卓玛措 明吉措姆 赛悟杰 仁增平措 尼玛次仁 Gezhi Jia;Zhou Yangcuo;Zhuoma Cuo;Mingji Cuomu;Saiwu Jie;Pingcuo Renzeng;Ciren Nima(Xizang University of Tibetan Medicine,Lhasa 850000,China;Tibetan Medicine Hospital of Jianzha County,Jianzha 811299,China;Qinghai Nationalities University-School of Foreign Languages,Xining 810000,China)

机构地区：[1]西藏藏医药大学研究生处,拉萨850000 [2]尖扎县藏医院,尖扎811299 [3]青海民族大学外国语学院,西宁810000

出　　处：《世界科学技术-中医药现代化》2022年第12期4817-4824,共8页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家科学技术部国家重点研发项目(2019YFC1712400):经典藏药如意珍宝片和白脉软膏治疗藏医重大疾病白脉病的示范开发研究,负责人:明吉措姆;2022年西藏藏医药大学博士点建设及中药学博士点培育项目(BSDJS2022007):藏医药治疗查龙病的用药规律研究,负责人:格知加。

摘　　要：目的 通过了解经典藏药白脉软膏的配伍特点及治疗白脉病的核心药物,为藏医临床治疗白脉病和新药研发提供参考。方法 对白脉软膏各成分药的味、化味、性效、入方率进行统计,建立数据库;通过查阅《长寿珠串》等藏医药经典古文献,选出20首常用白脉病的方剂药,统计白脉软膏各成分药在20首方剂内的单味药和药对频次。结果 发现白脉软膏的各成分药中姜黄、藏茴香、山奈入药量最大,药味以“甘味”、“辛味”、“苦味”为主,化味以“苦化味”为主,药性以“温”为主,效能以“凉”、“糙”、“轻”为主。白脉软膏各成分药在20首白脉病的常用方剂中麝香、白豆蔻、甘草的使用频次最多,在药对组中麝香、白豆蔻、甘草的两对组合的频次和支持度最大。结论 白脉软膏是以温补、活血、通络、行气、消炎为主的配伍组方,主要治疗白脉病,其核心成分为麝香、白豆蔻、甘草。Objective To study the compatibility characteristics of classical Tibetan medicine Baimai ointment and the core drugs in the treatment of baimai disease,and to provide reference for clinical treatment of baimai disease and new drug development.Methods A database was established on the taste,efficacy and dosage rate of each ingredient of Baimai ointment,and 20 commonly used prescriptions for baimai disease were selected by referring to the classical literatures of Tibetan medicine and literature of Tibetan medicine,and the single drug and drug pair frequency of each ingredient of Baimai ointment in 20 drugs were counted.Results It was found that among the ingredients of Baimai ointment,turmeric and Tibetan fennel had the largest dosage,and the main taste was "sweet taste","spicy taste" and "bitter taste".After taste to "bitter taste",mainly,The nature is mainly "warm",and the efficacy is mainly "cool","rough" and "light".Among the 20 commonly used prescriptions for white vein disease,musk,cardamom and glycyrrhiza were used the most frequently,and the combination of musk,cardamom and glycyrrhiza had the highest frequency and support in the drug pair group.Conclusion Baimai ointment is a combination of warming and tonifying,activating blood circulation,dredge collaterals,activating qi and reducing inflammation.The main medicine for baimai disease is musk,white cardamom and licorice.

关 键 词：白脉软膏 配伍特点 核心药物 

分 类 号：R289.1[医药卫生—方剂学]