Menin是组蛋白H3K79me2修饰的识别蛋白  

Menin,the COMPASS to locate H3K79 dimethylation

作　　者：周钦超 熊俊 朱冰 Qinchao Zhou;Jun Xiong;Bing Zhu(National Laboratory of Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China;College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China)

机构地区：[1]National Laboratory of Biomacromolecules,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China [2]College of Life Sciences,University of Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Science Bulletin》2023年第6期565-567,M0003,共4页科学通报（英文版）

基　　金：supported by the National Natural Science Foundation of China (32288102);the K.C.Wong Educational Foundation (GJTD-2020-06);the Youth Innovation Promotion Association (2020097) of the Chinese Academy of Sciences。

摘　　要：Eukaryotes package their DNA into chromatin with histones. An ever-growing number of histone post-translational modifications have been discovered, which facilitate and modulate chromatinbased fundamental processes, such as transcription, DNA damage repair, and DNA replication. Lysine residues are the most modified histone residues. Acetylation and methylation on lysine residues are the two most studied histone modifications, and they differ greatly in one biophysical property.

关 键 词：PROPERTY RESIDUES DAMAGE 

分 类 号：Q343.2[生物学—遗传学]