双针技术在甲状腺胶质样囊肿聚桂醇硬化治疗中的应用  

Application of dual-needle puncture technique in sclerotherapy using lauromacrogol for thyroid glioid cysts

作　　者：邱秀萍 张婷 张桔顺 黄汝哨 陈阳[1] 涂梅[1] 李仕海[3] 邱思花[2] QIU Xiuping;ZHANG Ting;ZHANG Jushun;HUANG Rushao;CHEN Yang;TU Mei;LI Shihai;QIU Sihua(Department of Endocrinology,Longyan Municipal First Hospital,Fujian Medical University,Fujian Province 364000,China)

机构地区：[1]龙岩市第一医院内分泌科,福建龙岩364000 [2]龙岩市第一医院超声科,福建龙岩364000 [3]龙岩市第一医院麻醉科,福建龙岩364000

出　　处：《介入放射学杂志》2023年第3期237-239,共3页Journal of Interventional Radiology

基　　金：福建省自然科学基金项目(2020J0112)。

摘　　要：目的 观察双针技术在甲状腺胶质样囊肿聚桂醇硬化治疗中的应用。方法 纳入龙岩市第一医院甲状腺胶质样囊肿患者80例,随机分为2组,每组40例。一组采用双针技术进行聚桂醇囊肿硬化治疗(双针组),另一组采用单针穿刺进行聚桂醇囊肿硬化治疗(单针组)。观察治疗后两组患者囊腔体积变化、疗效及不良反应。结果 术前2组患者年龄、性别、结节部位及结节体积差异均无统计学意义(均P>0.05)。术后1、3、6、12个月,双针组患者囊腔体积分别为(12.10±1.92)、(10.69±7.63)、(10.51±6.50)和(10.66±5.95)cm^(3),单针组患者囊腔体积分别为(13.18±2.08)、(16.47±11.51)、(14.41±10.99)和(13.41±10.89) cm^(3),差异有统计学意义(t=3.577、3.557、3.293、3.099,均P<0.05)。双针组有效率为90%(36/40),单针组有效率为72.5%(29/40),差异有统计学意义(χ^(2)=4.02,P<0.05)。两组不良反应发生率比较,差异无统计学意义(χ^(2)=0.125,P>0.05)。结论 双针技术在甲状腺胶质样囊肿聚桂醇硬化治疗中效果好于单针技术,值得临床推广使用。Objective To evaluate the application of dual-needle puncture technique in sclerotherapy using lauromacrogol for thyroid glioid cysts.Methods A total of 80 patients with thyroid glioid cysts,who were admitted to the Longyan Municipal First Hospital of China to receive treatment,were randomly divided into dual-needle puncture group(dual-needle group,n=40)and single-needle puncture group(single-needle group,n=40).The patients of dual-needle group received lauromacrogol sclerotherapy with dual-needle puncture technique,while the patients of single-needle group received lauromacrogol sclerotherapy with single-needle puncture technique.The postoperative volume changes of thyroid glioid cysts,curative efficacy,and adverse reactions were compared between the two groups.Results Before treatment,there were no statistically significant differences in age,gender,nodule location and nodule volume between the two groups(P>0.05).The postoperative 1-,3-,6-and 12-month nodule volumes in the dual-needle group were(12.10±1.92)cm^(3),(10.69±7.63)cm^(3),(10.51±6.50)cm and(10.66±5.95)cm^(3)respectively,which in the single-needle group were(13.18±2.08)cm^(2),(16.47±11.51)cm^(3),(14.41±10.99)cm^(3)and(13.41±10.89)cm^(3)respectively,the differences between the two groups were statistically significant(t=3.577,t=3.557,t=3.293 and t=3.099 respectively,all P<0.05).The effective rates in the dual-needle group and the single-needle group were 90%(36/40)and 72.5%(29/40)respectively,the difference between the two groups was statistically significant(χ^(2)=4.02,P<0.05).No statistically significant difference in the incidence of adverse reactions existed between the two groups(χ^(2)=0.125,P>0.05).Conclusion In treating thyroid glioid cysts with lauromacrogol sclerotherapy,the use of dual-needle puncture technique is superior to the use of single-needle puncture technique in curative effect.Therefore,dual-needle puncture technique is worth popularizing in clinical practice.

关 键 词：甲状腺胶质样囊肿 聚桂醇 硬化治疗 双针技术 

分 类 号：R581[医药卫生—内分泌]