辐射损伤防治药物研究进展  

Research progress of irradiation injuries anti-agents

作　　者：杜亚南 杨雪莹[1] 曾强[1] Du Yanan;Yang Xueying;Zeng Qiang(Institute for Occupational Health,Tianjin Centers for Disease Control and Prevention,Tianjin 300011,China)

机构地区：[1]天津市疾病预防控制中心职业健康研究所,天津300011

出　　处：《中华劳动卫生职业病杂志》2023年第3期237-240,共4页Chinese Journal of Industrial Hygiene and Occupational Diseases

基　　金：天津市医学重点学科(专科)建设项目(TJYXZDXK-066B);天津市卫生健康科研项目(TJWJ2022XK040)。

摘　　要：辐射损伤防治药物是指能抑制辐射损伤的发生,或者在照射后早期使用减轻辐射损伤的发展,促进损伤恢复的药物。根据作用机制和干预时间,将辐射损伤的防治药物分为4类,即外辐射暴露的防护药、缓解药、治疗药以及放射性核素内污染防治药。本文对近年来辐射损伤防治药的研究进展进行综述。Irradiation injuries anti-agents refer to drugs that can inhibit the initial stage of radiation injuries,or reduce the development of radiation injuries and promote the recovery of injuries when used early after irradiation exposure.According to the mechanism of action and the time of intervention,the irradiation injuries anti-agents are divided into four categories:radioprotectors,radiomitigators,radiation therapeutics for external radiation exposure,and anti-agents for internalized radionuclides.In this paper,the research progress of irradiation injuries anti-agents in recent years is reviewed.

关 键 词：辐射 电离 辐射损伤 辐射防护剂 辐射损伤缓解药 辐射损伤治疗药 放射性核素内污染防治药 

分 类 号：R818.05[医药卫生—放射医学]