3%聚多卡醇联合无水乙醇硬化治疗肢体静脉畸形的效果  

The clinical effect of DSA-guided percutaneous sclerotherapy using 3%polidocanol combined with absolute ethanol in the treatment of venous malformation of limbs

作　　者：王世知[1] 赵文鹏 周为民[1] WANG Shizhi;ZHAO Wenpeng;ZHOU Weimin(Department of Vascular Surgery,Second Affiliated Hospital of Nanchang University,Nanchang,Jiangxi Province 330006,China)

机构地区：[1]南昌大学第二附属医院血管外科,江西南昌330006

出　　处：《介入放射学杂志》2023年第2期123-126,共4页Journal of Interventional Radiology

基　　金：江西省教育厅科学技术研究项目(GJJ20097)。

摘　　要：目的 探讨DSA导引下经皮注射3%聚多卡醇联合无水乙醇治疗肢体静脉畸形的临床效果。方法 收集2019年7月至2020年7月南昌大学第二附属医院收治的32例肢体静脉畸形患者临床资料。其中男12例,女20例,年龄10~52岁。根据术前MRI检查和术中血管造影,Puig分型Ⅰ型6例,Ⅱ型20例,Ⅲ型3例,Ⅳ型3例。所有患者均在局部麻醉下接受3%聚多卡醇联合无水乙醇硬化治疗。术后4周复查MRI,记录病灶大小并计算病灶缩小率。随访6~12个月。结果 32例中26例为低回流型静脉畸形,6例为高回流型静脉畸形。术后6例PuigⅠ型患者治愈,20例Ⅱ型患者基本治愈,6例Ⅲ、Ⅳ型患者均有效,治疗有效率为100%。出现局部张力性水泡2例,局部色素沉着3例,未出现皮肤坏死表现。结论3%聚多卡醇联合无水乙醇硬化治疗肢体静脉畸形安全有效,并发症较少。ObjectiveTo investigate the clinical effect of DSA-guided percutaneous injection of 3%polidocanol and absolute ethanol in the treatment of venous malformation of limbs.MethodsThe clinical data of 32 patients with venous malformation of limbs,who were treated in the Second Affiliated Hospital of Nanchang University of China between July 2019 and July 2020,were collected.The 32 patients included 12 males and 20 females,aged 10-52 years.According to preoperative MRI and intraoperative angiography findings,6 patients were of Puig typeⅠ,20 patients were of Puig typeⅡ,3 patients were of Puig typeⅢand 3 patients were of Puig typeⅣ.Under local anesthesia,percutaneous sclerotherapy using 3%polidocanol combined with absolute ethanol was carried out in all patients.MRI reexamination was performed 4 weeks after treatment.The size of lesion was measured and the lesion reduction rate was calculated in all patients.The patients were followed up for 6-12 months.ResultsAmong the 32 patients,low-reflux type of venous malformation was seen in 26 and high-reflux type of venous malformation in 6.After sclerotherapy,6 patients with Puig typeⅠwere cured,20 patients with Puig typeⅡwere basically cured,and 6 patients with Puig typeⅢorⅣobtained effective results,with an effective rate of 100%.Two patients developed local tension blisters and three patients developed local pigmentation.No signs of skin necrosis were observed.ConclusionFor the treatment of venous malformation of limbs,percutaneous sclerotherapy using 3%polidocanol combined with absolute ethanol is clinically safe and effective with less complications.

关 键 词：静脉畸形 硬化疗法 聚多卡醇 无水乙醇 

分 类 号：R543[医药卫生—心血管疾病]