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作 者:俞萍萍 周志国 YU Pingping;ZHOU Zhiguo(Department of Pharmacy,Conch Hospital of Anhui Medical University,Wuhu 241000,China;Surgical Department,Wanzhi District General Hospital,Wuhu 241100,China)
机构地区:[1]安徽医科大学附属海螺医院药剂科,安徽芜湖241000 [2]芜湖市湾沚区总医院外科,安徽芜湖241100
出 处:《基层中医药》2023年第3期30-34,共5页Basic Traditional Chinese Medicine
摘 要:目的 探讨三黄汤加味促进湿热下注型混合痔术后患者创口愈合的机制及防治出血的效果。方法 选取2021年3月—2022年3月经本院收治的45例湿热下注型混合痔术后患者,依据随机数字表法将患者分为对照组与观察组,对照组23例、观察组22例。对照组术后采用常规治疗与换药,观察组在治疗组基础上服用三黄汤加味治疗。观察两组患者治疗后的疗效、临床症状、中医证候积分和实验室检查,包括白细胞计数(WBC)、淋巴细胞计数(LYM)、中性粒细胞计数(NEU)。结果 治疗后,观察组患者的临床总有效率与对照组相比较高;治疗期间,观察组患者疼痛消失时间、创面愈合时间、出血停止时间均短于对照组;与治疗前比,治疗后两组患者疼痛、肛周脓肿、坠胀感评分、WBC、LYM、NEU水平均降低,其中观察组低于对照组,差异有统计学意义(P<0.05)。结论 三黄汤加味联合常规治疗可有效减轻混合痔术后患者的炎症反应,提高患者的临床疗效,减轻疼痛、减少出血、加快创口愈合,改善中医症状。Objective To explore the mechanism of Supplemented Sanhuang Decoction promoting wound healing of patients with mixed hemorrhoid of dampness-heat pouring down pattern after surgery and the effect on bleeding.Methods A total of 45 eligible patients were treated in our hospital from March 2021 to March 2022 were selected and randomized into the control group(n=23)and the observation group(n=22)with the random number table method.Routine therapy and dressing were adopted in the control after operation,while the observation group was treated with routine therapy,dressing,and Supplemented Sanhuang Decoction.The effect,symptoms,TCM syndrome score,and laboratory test results[white blood cell count(WBC),lymphocyte count(LYM),and neutrophil count(NEU)]before and after treatment were compared between the two groups.Results After treatment,the total clinical effective rate in the observation group was higher than that in the control group.During the treatment,the pain disappearance,wound healing,and hemostasis in the observation group were earlier than those in the control group.The scores of the pain,perianal abscess,and depression and distension,and levels of WBC,LYM,and NEU were lower than those before treatment in the two groups,and they were lower in the observation group than in the control group(P<0.05).Conclusion Supplemented Sanhuang Decoction combined with conventional treatment can alleviate the inflammatory response,pain,bleeding,and TCM symptoms in patients with mixed hemorrhoid after surgery,improve the clinical efficacy,and accelerate wound healing.
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