综合化学实验:一种功能化穴醚的合成及结构分析  

A Comprehensive Chemical Experiment:Synthesis and Structural Analysis of A Functionalized Cryptate

作　　者：周密 胡博文 宋柳 袁果园[1] 李平 周倩羽 ZHOU Mi;HU Bo-wen;SONG Liu;YUAN Guo-yuan;LI Ping;ZHOU Qian-yu(College of Chemistry and Chemical Engineering,Chongqing University of Science and Technology,Chongqing 401331,China)

机构地区：[1]重庆科技学院化学化工学院,重庆401331

出　　处：《广州化工》2023年第3期256-258,共3页GuangZhou Chemical Industry

基　　金：重庆市博士“直通车”科研项目(No:sl202100000097);重庆科技学院人才启动基金(No:ckrc2021028)。

摘　　要：穴醚具有三维的分子空腔,可以高选择性的识别客体分子,因此在超分子化学领域占有非常重要的地位。但是对于学生来说,基于本科阶段的化学知识和实验水平,很难简单高效的合成穴醚分子。在这里,推荐一个通过醛胺缩合和硼氢化钠还原反应串联,以构筑一种功能化穴醚分子的实验。本实验充分运用了相关理论知识和实验技能,不仅可以提高学生的综合能力,同时还能锻炼学生的创新能力及科学素养。Due to the three dimensional molecular cavity of cryptate,it shows high selectivity toward guest molecule,therefore,it occupies a very important position in supramolecular chemistry.However,based on undergraduate chemistry knowledge and experimental level,it is difficult to synthesize cryptate through simple and efficient method.Herein,an experiment was recommended to synthesize a functionalized cryptate via coupling two reactions.The related theoretical knowledge and experimental skills were made full used,it may cultivate students'comprehensive experimental ability,moreover,it could improve the innovation ability and scientific literacy.

关 键 词：功能化穴醚 席夫碱 还原反应 综合化学实验 

分 类 号：G642[文化科学—高等教育学]