低共熔溶剂体系提取中药渣中肉桂醛  

Extracting cinnamaldehyde from herb residue in deep eutectic solvent system

作　　者：张荣清 刘云云 陈海峰[1] 陈小燕[2] 张宇[2] 邱雨心 ZHANG Rong-qing;LIU Yun-yun;CHEN Hai-feng;CHEN Xiao-yan;ZHANG Yu;QIU Yu-xin(School of Mechanical and Electrical Engineering,Shaanxi University of Science and Technology,Xi′an 710021,Shaanxi Province,China;Key Laboratory of Renewable Energy,Chinese Academy of Sciences,Guangzhou Institute of Energy,Chinese Academy of Sciences,Guangzhou 510640,Guangdong Province,China)

机构地区：[1]陕西科技大学机电工程学院,陕西西安710021 [2]中国科学院广州能源研究所中国科学院可再生能源重点实验室,广东广州510640

出　　处：《化学工程》2023年第4期22-27,共6页Chemical Engineering(China)

基　　金：国家重点研发计划课题(2019YFC1906602);陕西省自然科学基础研究计划面上项目(2021JM-382)。

摘　　要：筛选适合的低共熔溶剂(DES)对中药渣疏水性功效成分进行高效提取对提高中药固废物的资源化利用效率有着重要的意义。采用微波辅助低共熔溶剂法对肉桂枝中药渣原料中的肉桂醛进行提取,考察低共熔溶剂类别、固液比、提取时间、摩尔比、提取温度等因素对肉桂醛提取率的影响。结果表明:氯化胆碱与乙二醇组成的DES体系中,在氯化胆碱与乙二醇摩尔比为1∶6、固液质量体积比1∶60、提取温度100℃、反应时间90 min的较优条件下肉桂醛的提取率可达到12.64 mg/g,相比传统甲醇提取法提取率增加了45.45%。中性DES相比酸性DES对功效成分的稳定性和提取效率都具有较佳的效果。氯化胆碱和乙二醇中性DES有益于中药渣功效成分的提取和纯化,具有较大的发展潜力。For efficient extraction of hydrophobic functional components from Chinese medicine residues,it is important to screen a suitable Deep Eutectic Solvent(DES),which can improve the resource utilization efficiency of Chinese medicine solid wastes.The cinnamaldehyde in the cinnamon twig residues was extracted by microwave-assisted deep eutectic solvent method.The effects of deep eutectic solvent type,solid-liquid ratio,extraction time,molar ratio,extraction temperature and other conditions on the extraction rate of cinnamaldehyde were investigated.The results show that the most efficient extraction rate of cinnamaldehyde is 12.64 mg/g after reaction at 100℃for 90 min with choline chloride/glycol(molar ratio of 1∶6)and the solid-liquid mass volume ratio of 1∶60.It is found that the extraction rate increases by 45.45%compared with the traditional methanol extraction method.Compared with acidic DES,Neutral DES has better effect on the stability and extraction efficiency of active ingredients.The use of neutral choline chloride/glycol DES is conductive to improve the extraction and purification of active components from Chinese medicine residue,and has great development potential.

关 键 词：中药渣 DES 肉桂醛 

分 类 号：TQ28[化学工程—有机化工]