Improving hydroxyapatite coating ability on biodegradable metal through laser-induced hydrothermal coating in liquid precursor:Application in orthopedic implants  

作　　者：Jaeho Park Seung-Hoon Um Youngmin Seo Jaehong Lee Yu-Chan Kim Myoung-Ryul Ok Suk-Won Hwang Jeong-Yun Sun Hyung-Seop Han Hojeong Jeon 

机构地区：[1]Biomaterials Research Center,Biomedical Research Division,Korea Institute of Science and Technology(KIST),Seoul,02792,South Korea [2]Department of Materials Science and Engineering,Seoul National University(SNU),Seoul,08826,South Korea [3]Division of Biomedical Science and Technology,KIST School,Korea University of Science and Technology,Seoul,02792,South Korea [4]KU-KIST Graduate School of Converging Science and Technology,Korea University,Seoul,02841,South Korea

出　　处：《Bioactive Materials》2023年第7期796-806,共11页生物活性材料（英文）

基　　金：This work was supported by a National Research Foundation of Korea(NRF)grant funded by the Korean government(MSIT)[grant number 2020R1A2C2010413];Korea Research Council[grant number NRF-2021K1A3A1A74095929];KIST project[grant number 2E31641];KU-KIST Graduate School of Converging Science and Technology Program.

摘　　要：During the past decade,there has been extensive research toward the possibility of exploring magnesium and its alloys as biocompatible and biodegradable materials for implantable applications.Its practical medical application,however,has been limited to specific areas owing to rapid corrosion in the initial stage and the consequent complications.Surface coatings can significantly reduce the initial corrosion of Mg alloys,and several studies have been carried out to improve the adhesion strength of the coating to the surfaces of the alloys.The composition of hydroxyapatite(HAp)is very similar to that of bone tissue;it is one of the most commonly used coating materials for bone-related implants owing to favorable osseointegration post-implantation.In this study,HAp was coated on Mg using nanosecond laser coating,combining the advantages of chemical and physical treatments.Photothermal heat generated in the liquid precursor by the laser improved the adhesion of the coating through the precipitation and growth of HAp at the localized nanosecond laser focal area and increased the corrosion resistance and cell adhesion of Mg.The physical,crystallographic,and chemical bondings were analyzed to explore the mechanism through which the surface adhesion between Mg and the HAp coating layer increased.The applicability of the coating to Mg screws used for clinical devices and improvement in its corrosion property were confirmed.The liquid environment-based laser surface coating technique offers a simple and quick process that does not require any chemical ligands,and therefore,overcomes a potential obstacle in its clinical use.

关 键 词：Biodegradable metal HAp coating Nanosecond laser Photothermal synthesis Soret effect(thermophoresis) 

分 类 号：TG174.4[金属学及工艺—金属表面处理]