高脂血症性重症胰腺炎与胆源性急性重症胰腺炎的临床特点比较  

Comparison of Clinical Features between Hyperlipidemic Severe Acute Pancreatitis and Biliary Severe Acute Pancreatitis

作　　者：叶思婷 顾忠民[1] 江贤威[1] 陈超[1] YE Siting;GU Zhongmin;JIANG Xianwei;CHEN Chao(Department of Critical Care Medicine,Fuzhou Second Hospital,Fuzhou,Fujian Province,350007 China)

机构地区：[1]福州市第二医院重症医学科,福建福州350007

出　　处：《中外医疗》2022年第33期14-17,共4页China & Foreign Medical Treatment

基　　金：福州市临床重点专科建设项目经费资助(201912001);福建省创伤骨科急救与康复临床医学研究中心(2020Y2014)。

摘　　要：目的探讨高脂血症性重症胰腺炎(hyperlipidemia severe acute pancreatitis,HLSAP)的临床特点。方法回顾性选取2015年1月-2019年12月福州市第二医院收治的HLSAP患者47例(HLSAP组)与同期收治的胆源性重症胰腺炎(biliary severe acute pancreatitis,BSAP)患者39例(BSAP组)。比较两组患者的临床特点。结果HLSAP组发病年龄低于BSAP组[42(34,47)岁vs 66(57,77)岁],差异有统计学意义(Z=-6.218,P<0.001)。HLSAP组患者的TG、TC、CRP均高于BSAP组,差异有统计学意义(P<0.05)。HLSAP组患者的AMY、AST、ALT均低于BSAP组,差异有统计学意义(P<0.001)。HLSAP组合并糖尿病、酮症酸中毒、脂肪肝、胰腺局部并发症发生率均高于BSAP组,差异有统计学意义(χ^(2)=6.865、5.441、18.603、5.446,P<0.05)。结论HLSAP与BSAP在临床特征上存在一定差异性,HLSAP患者发病年龄更低,血淀粉酶升高不明显,常合并糖尿病、脂肪肝,更易出现胰腺局部并发症。Objective To investigate the clinical characteristics of hyperlipidemia severe acute pancreatitis(HLSAP).Methods Retrospective selected 47 patients with HLSAP admitted to the Fuzhou Second Hospital from January 2015 to December 2019(HLSAP group)and 39 patients with biliary severe acute pancreatitis(BSAP)(BSAP group)admitted during the same period.The clinical features of the two groups of patients were compared.Results The onset age[42(34,47)]years old vs[66(57,77)]years old of HLSAP group was lower than the BSAP group,and the difference was statistically significant(Z=-6.218,P<0.001).The TG,TC and CRP of patients in HLSAP group were higher than those in BSAP group,the difference was statistically significant(P<0.05).The levels of AMY,AST and ALT in HLSAP group were significantly lower than those in BSAP group,the difference was statistically significant(P<0.001).The incidence of local complications of diabetes,ketoacidosis,fatty liver and pancreas in HLSAP group was higher than that in BSAP group,the difference was statistically significant(χ^(2)=6.865,5.441,18.603,5.446,P<0.05).Conclusion There are some differences in clinical characteristics between HLSAP and BSAP.HLSAP patients have a lower age of onset,no obvious increase in blood amylase,and are often complicated with diabetes and fatty liver,and are more likely to have local pancreatic complications.

关 键 词：高脂血症性重症胰腺炎 重症胰腺炎 高脂血症 

分 类 号：R5[医药卫生—内科学]