全凭Sev吸入麻醉与Pro静脉麻醉对行急性阑尾炎患儿手术期间麻醉起效时间及苏醒时间的影响对比  

Comparison of the Effects of Full Sev Inhalation Anesthesia and Pro Intravenous Anesthesia on the Onset of Anesthesia and Wake-up Time during Surgery for Children with Acute Appendicitis

作　　者：周昶碧[1] 许德明[1] 许金远 ZHOU Changbi;XU Deming;XU Jinyuan(Department of Anesthesiology,Affiliated Hospital of Putian University,Putian,Fujian Province,351100 China)

机构地区：[1]莆田学院附属医院麻醉科,福建莆田351100

出　　处：《中外医疗》2022年第34期15-19,共5页China & Foreign Medical Treatment

摘　　要：目的对比观察全凭七氟醚(sevoflurane,Sev)吸入麻醉与丙泊酚(propofol,Pro)静脉麻醉对行急性阑尾炎患儿手术期间麻醉起效时间及苏醒时间的影响。方法简单随机选取2020年2月-2022年2月莆田学院附属医院儿科收治的60例接受手术治疗的急性阑尾炎患儿为研究对象,按照麻醉方法进行分组,研究组中30例患儿采用全凭Sev吸入麻醉,对照组中30例患儿采用Pro静脉麻醉。比较两组手术期间麻醉起效时间、睫毛反射消失时间、Ramsay镇静评分、血流动力学指标、苏醒时间及术后不良反应发生率。结果研究组麻醉起效时间(88.7±11.6)s、睫毛反射消失时间(45.3±6.4)s、苏醒时间(19.3±3.6)min均短于对照组(131.9±17.2)s、(58.5±7.1)s、(26.9±1.4)min,且研究组Ramsay评分(3.1±0.8)分高于对照组(2.5±0.5)分,差异有统计学意义(t=11.405、7.564、10.777、3.484,P<0.05)。两组患儿T1时的MAP、SaO_(2)、HR水平比较,差异无统计学意义(P>0.05);T2时的MAP、SaO_(2)、HR水平均有所降低,T3时的MAP、SaO_(2)、HR水平均有所上升。对照组T2、T3时的MAP水平均高于研究组,SaO_(2)水平高于对照组,T3时的HR水平高于对照组,T2时的HR水平低于对照组,差异有统计学意义(P<0.05)。两组术后不良反应发生率(3.33%vs 16.67%)比较,差异无统计学意义(χ^(2)=1.667,P>0.05)。结论对于急性阑尾炎行手术治疗的患儿,全凭Sev吸入麻醉的起效快,对血流动力学指标影响小,苏醒快,较Pro静脉麻醉的麻醉效果更安全可靠。Objective To compare the effects of full sevoflurane(Sev)inhalation anesthesia and propofol(Pro)intravenous anesthesia on the onset of anesthesia and wake-up time during surgery in children with acute appendicitis.Methods 60 children with acute appendicitis who received surgical treatment from the Department of Pediatrics of the Affiliated Hospital of Putian University from February 2020 to February 2022 were randomly selected as the study subjects.They were grouped according to the anesthesia method.In the study group,30 children were treated with Sev inhalation anesthesia,while in the control group,30 children were treated with Pro intravenous anesthesia.The onset time of anesthesia,disappearance time of eyelash reflex,Ramsay sedation score,hemodynamic indexes,recovery time and incidence of postoperative adverse reactions were compared between the two groups.Results The onset time of anesthesia(88.7±11.6)s,the disappearance time of eyelash reflex(45.3±6.4)s,and the awakening time(19.3±3.6)min in the study group were shorter than those in the control group(131.9±17.2)s,(58.5±7.1)s,and(26.9±1.4)min,and the Ramsay score(3.1±0.8)points in the study group was higher than that in the control group(2.5±0.5)points,the difference was statistically significant(t=11.405,7.564,10.777,3.484,P<0.05).There was no statistically significant difference between the two groups in MAP,SaO_(2) and HR levels at T1(P>0.05).The levels of MAP,SaO_(2) and HR at T2 decreased,and the levels of MAP,SaO_(2) and HR at T3 increased.The levels of MAP and HR at T2 and T3 in the control group were higher than those in the study group,SaO_(2) level was higher than the control group,HR level at T3 was higher than the control group,and HR level at T2 was lower than the control group,the difference was statistically significant(P<0.05).Conclusion For children undergoing surgery for acute appendicitis,full Sev inhalation anesthesia has a faster onset,less impact on hemodynamic indexes,quicker awakening,and a safer and more reliable anesthetic

关 键 词：全凭Sev吸入麻醉 麻醉起效时间 Pro静脉麻醉 苏醒时间 小儿急性阑尾炎 

分 类 号：R969[医药卫生—药理学]