血管生成素样蛋白4与糖尿病及糖尿病肾脏疾病关系的研究进展  

Research progress in the relationship between ANGPTL4 and diabetes mellitus and diabetic kidney disease

作　　者：汪蓉 胡雪剑[2] 任建功[2] WANG Rong;HU Xuejian;REN Jiangong(The Second Clinical Medical College of Lanzhou University,Lanzhou 730000,China)

机构地区：[1]兰州大学第二临床医学院,:730000 [2]兰州大学第二医院内分泌代谢科,:730000

出　　处：《中国糖尿病杂志》2023年第3期229-231,共3页Chinese Journal of Diabetes

摘　　要：血管生成素样蛋白4(ANGPTL4)作为血脂水平的重要调节因子,不仅调节脂质代谢,还影响糖代谢,参与体内氧化应激及炎症反应。DM及DKD患者ANGPTL4水平常发生改变。本文综述对ANGPTL4与DM及DKD关系的研究进展。Angiopoietin like protein 4(ANGPTL4),as an important regulator of blood lipid level,not only regulates lipid metabolism,but also affects glucose metabolism,and participates in oxidative stress and inflammatory response in vivo.ANGPTL4 levels often changed in diabetes mellitus(DM)and diabetic kidney disease(DKD)patients.This paper reviews the research progress on the relationship between ANGPTL4,DM and DKD.

关 键 词：血管生成素样蛋白4 糖尿病肾脏疾病 研究进展 

分 类 号：R587.2[医药卫生—内分泌] R692.9[医药卫生—内科学]