漯河市某医院2016—2020年常见细菌耐药性监测报告  

Monitoring report on drug resistance of common bacteria in a general hospital in Luohe from 2016 to 2020

作　　者：常军玲 曹兴华[1] 李宁 孟艳平[1] 苗辉[2] 吴昊 Chang Junling;Cao Xinghua;Li Ning;Meng Yanping;Miao Hui;Wu Hao(Department of Laboratory,Luohe Central Hospital,Luohe 462000,China;Department of Laboratory,Zhengzhou Third People’s Hospital,Zhengzhou 450099,China;Department of Nosocomial Infection,Luohe Central Hospital,Luohe 462000,China)

机构地区：[1]漯河市中心医院检验科,漯河462000 [2]郑州市第三人民医院检验科,郑州450099 [3]漯河市中心医院院感科,漯河462000

出　　处：《中国实用医刊》2023年第2期44-48,共5页Chinese Journal of Practical Medicine

摘　　要：目的了解漯河市某医院5年间常见细菌的耐药情况,为临床合理应用抗菌药物提供数据支持。方法分析漯河市中心医院2016年1月至2020年12月样本中检出的所有非重复菌株,应用WHONET 5.6软件进行统计分析。结果共分离细菌11133株,其中革兰阳性菌占39.5%(4476/11333),革兰阴性菌占60.5%(6858/11333)。苛养菌检出尤为突出,肺炎链球菌和流感嗜血杆菌占比较高,主要来自0~5岁患儿,耐青霉素肺炎链球菌显著下降;耐碳氢酶烯类细菌中大肠埃希菌平稳在2.2%~2.4%,肺炎克雷伯菌和铜绿假单胞菌呈下降趋势,分别降至28.3%和18.3%,而鲍曼不动杆菌从66.2%升至89.6%;耐甲氧西林的金黄色葡萄球菌呈下降趋势,降至41.6%,未见万古霉素和利奈唑胺耐药菌株。结论医院耐药形势严峻,应多部门相互协作以遏制耐药细菌流行播散,持续做好细菌耐药性监测工作,为临床合理使用抗菌药物提供依据。Objective To investigate the drug resistance of common bacteria in a general hospital in Luohe in 5 years,and to provide data support for rational clinical use of antibiotics.Methods All non repetitive strains deteced in the sample from Luohe Central Hospital from January 2016 to December 2020 were analyzed,and statistical analysis was conducted with WHONET 5.6 software.Results A total of 11133 strains were isolated from samples,of which 39.5%(4476/11333)were Gram positive bacteria,and of which 60.5%(6858/11333)were Gram negative bacteria.The detection of fastidious bacteria was particularly prominent;Streptococcus pneumoniae and Haemophilus influenzae accounted for a high proportion,mainly in samples from children aged 0-5 years;proportion of penicillin resistant Streptococcus pneumoniae decreased significantly.Among the hydrocarbon enzyme resistant bacteria,Escherichia coli was stable at 2.2%-2.4%,proportion of Klebsiella pneumoniae and Pseudomonas aeruginosa showed a downward trend,falling to 28.3%and 18.3%respectively,while Acinetobacter baumannii rose from 66.2%to 89.6%.Proportion of methicillin resistant Staphylococcus aureus showed a downward trend,decreased by 41.6%,and no vancomycin or linezolid resistant strains was found.Conclusions The situation of drug resistance in hospital is serious.It is necessary to cooperate with multiple departments to curb the spread of drug resistant bacteria,and to continue to monitor bacterial drug resistance,so as to provide a basis for rational use of antibiotics in clinical practice.

关 键 词：细菌耐药 抗菌药物 肺炎链球菌 多重耐药菌 

分 类 号：R446.5[医药卫生—诊断学]