微通道反应高效合成3,4-二氯苯胺  

Efficient synthesis of 3,4-dichloroaniline through microchannel reaction

作　　者：阮浩华 严泽华 吴浩 吴文良 尹凯 RUAN Haohua;YAN Zehua;WU Hao;WU Wenliang;YIN Kai(Zhejiang Jitai New Materials Co.,Ltd.,Shaoxing 312369,Zhejiang,China;Zhejiang Nanjiao Chemistry Co.,Ltd.,Shaoxing 312369,Zhejiang,China;School of Chemistry and Chemical Engineering,Southeast University,Nanjing 211189,China)

机构地区：[1]浙江吉泰新材料股份有限公司,浙江绍兴312369 [2]浙江南郊化学有限公司,浙江绍兴312369 [3]东南大学化学化工学院,南京211189

出　　处：《世界农药》2023年第4期37-40,共4页World Pesticide

摘　　要：3,4-二氯苯胺是一种常用化工原料,可用于合成敌稗、敌草隆、利谷隆等农药,分散大红GA等染料,二氯苯基硫脲等医药。为了进一步提高反应转化率和生产效率,基于微通道反应,以3,4-二氯硝基苯为原料,经3%铂碳催化加氢合成3,4-二氯苯胺,并对反应温度、微通道反应模块数量和氢气压力等进行了优化研究。优化条件下,该工艺收率98%,产品含量>99.8%(GC),具有工业化应用前景与价值。3,4-Dichloroaniline is a common chemical raw material.It is used to synthesize herbicides such as paspalum,diuron and liguron,dyes such as disperse red GA,and medicines such as dichlorophenyl thiourea.In order to improve the conversion rate and production efficiency,the process route of catalytic hydrogenation of 3,4-dichloronitrobenzene to3,4-dichloroaniline by microchannel was developed.The total yield was over 98%,and purity was over 99.8% by GC.It has the prospect and value of industrialization.

关 键 词：3 4-二氯苯胺 微通道反应 合成 

分 类 号：TQ450.6[化学工程—农药化工]